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从乌拉圭一名慢性感染个体中获得的戊型肝炎病毒3型全基因组序列。

Complete Genome Sequence of Hepatitis E Virus Genotype 3 Obtained from a Chronically Infected Individual in Uruguay.

作者信息

Cancela Florencia, Panzera Yanina, Mainardi Victoria, Gerona Solange, Ramos Natalia, Pérez Ruben, Arbiza Juan, Mirazo Santiago

机构信息

Sección Virología, Facultad de Ciencias, Universidad de la República, Montevideo, Uruguay.

Sección Genética Evolutiva, Facultad de Ciencias, Universidad de la República, Montevideo, Uruguay.

出版信息

Microbiol Resour Announc. 2021 Jun 3;10(22):e0036721. doi: 10.1128/MRA.00367-21.

DOI:10.1128/MRA.00367-21
PMID:34080907
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8354548/
Abstract

Hepatitis E virus (HEV) is a leading cause of acute viral hepatitis worldwide. We report the full-length genome sequence of an HEV-3 strain obtained from a chronically infected patient from Uruguay. This strain shared only 86% nucleotide sequence identity with the most closely related reference strain belonging to subtype 3m.

摘要

戊型肝炎病毒(HEV)是全球急性病毒性肝炎的主要病因。我们报告了从一名来自乌拉圭的慢性感染患者身上获得的一株HEV-3毒株的全长基因组序列。该毒株与属于3m亚型的最密切相关参考毒株的核苷酸序列同一性仅为86%。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a24a/8354548/24c413890a26/mra.00367-21-f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a24a/8354548/24c413890a26/mra.00367-21-f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a24a/8354548/24c413890a26/mra.00367-21-f001.jpg

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Front Microbiol. 2021 Jan 28;11:634430. doi: 10.3389/fmicb.2020.634430. eCollection 2020.
2
Update: proposed reference sequences for subtypes of hepatitis E virus (species ).更新:戊型肝炎病毒(种)各亚型的建议参考序列。
J Gen Virol. 2020 Jul;101(7):692-698. doi: 10.1099/jgv.0.001435.
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Clinical Manifestations, Pathogenesis and Treatment of Hepatitis E Virus Infections.戊型肝炎病毒感染的临床表现、发病机制及治疗
J Clin Med. 2020 Jan 24;9(2):331. doi: 10.3390/jcm9020331.
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Molecular Evolutionary Genetics Analysis (MEGA) for macOS.用于 macOS 的分子进化遗传学分析(MEGA)。
Mol Biol Evol. 2020 Apr 1;37(4):1237-1239. doi: 10.1093/molbev/msz312.
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Locally Acquired Chronic Hepatitis E Followed by Epstein-Barr Virus Reactivation and Burkitt Lymphoma as a Suspected Extrahepatic Manifestation in a Liver Transplant Recipient.肝移植受者中出现的本地获得性慢性戊型肝炎,随后发生爱泼斯坦-巴尔病毒再激活及伯基特淋巴瘤,疑似为肝外表现。
Am J Case Rep. 2019 Jul 14;20:1016-1021. doi: 10.12659/AJCR.916253.
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