Furtunescu F L, Pistol A
"Carol Davila" University of Medicine and Pharmacy - Public Health and Management.
National Institute of Public Health - National Centre for Control and Surveillance of Communicable Diseases, Bucharest.
Acta Endocrinol (Buchar). 2020 Oct-Dec;16(4):479-486. doi: 10.4183/aeb.2020.479.
The COVID-19 pandemic affected 62 million people and caused more than 1.4 million deaths globally till the end of November 2020. Our study aimed to explore the association between obesity and the negative outcomes of COVID-19 worldwide. The prevalence of obesity and overweight per country was extracted from the World Health Organization information system and, for measuring the COVID-19 negative outcomes, we calculated the cumulated notification rate and the mortality for the interval since starting of pandemic till the 29 of November 2020. We explored the linear relationship between COVID-19 and obesity by a bivariate Spearman rank correlation, interpreted using the rule of thumb for 95% level of confidence. We found globally a positive, moderate, and statistically significant correlation between prevalence of obesity and overweight and the negative outcomes of COVID-19. Some of the results found at global level were confirmed in the disaggregated analysis per WHO regions. Due to the linear association of obesity with the COVID-19 negative outcomes, effective actions are needed for keeping the health systems resilience during the COVID-19. Preventing the obese and overweight people to be infected, prioritizing access to vaccination and to adequate care and treatment could be effective.
截至2020年11月底，新冠疫情已在全球影响了6200万人，并导致超过140万人死亡。我们的研究旨在探讨全球范围内肥胖与新冠疫情负面结果之间的关联。各国肥胖和超重的患病率数据取自世界卫生组织信息系统，为衡量新冠疫情的负面结果，我们计算了自疫情开始至2020年11月29日期间的累计通报率和死亡率。我们通过双变量Spearman等级相关性分析了新冠疫情与肥胖之间的线性关系，并根据95%置信水平的经验法则进行解读。我们发现，全球范围内肥胖和超重患病率与新冠疫情负面结果之间存在正相关、中等程度且具有统计学意义的关联。在按世界卫生组织区域进行的分类分析中，一些在全球层面得出的结果得到了证实。鉴于肥胖与新冠疫情负面结果之间存在线性关联，在新冠疫情期间需要采取有效行动以保持卫生系统的韧性。防止肥胖和超重人群感染、优先提供疫苗接种以及充分的护理和治疗可能会有效果。
