Africa Centre of Excellence in Coastal Resilience, University of Cape Coast, Cape Coast, Ghana.
Department of Fisheries and Aquatic Sciences, School of Biological Sciences, College of Agriculture and Natural Sciences, University of Cape Coast, Cape Coast, Ghana.
PLoS One. 2021 Mar 1;16(3):e0247274. doi: 10.1371/journal.pone.0247274. eCollection 2021.
The coronavirus 2019 (COVID-19) has overwhelmed the health systems of several countries, particularly those within the African region. Notwithstanding, the relationship between health systems and the magnitude of COVID-19 in African countries have not received research attention. In this study, we investigated the relationship between the pervasiveness of the pandemic across African countries and their Global Health Security Index (GHSI) scores.
The study included 54 countries in five regions viz Western (16); Eastern (18); Middle (8); Northern (7); and Southern (5) Africa. The outcome variables in this study were the total confirmed COVID-19 cases (per million); total recoveries (per million); and the total deaths (per million). The data were subjected to Spearman's rank-order (Spearman's rho) correlation to determine the monotonic relationship between each of the predictor variables and the outcome variables. The predictor variables that showed a monotonic relationship with the outcome were used to predict respective outcome variables using multiple regressions. The statistical analysis was conducted at a significance level of 0.05.
Our results indicate that total number of COVID-19 cases (per million) has strong correlations (rs >0.5) with the median age; aged 65 older; aged 70 older; GDP per capita; number of hospital beds per thousand; Human Development Index (HDI); recoveries (per million); and the overall risk environment of a country. All these factors including the country's commitments to improving national capacity were related to the total number of deaths (per million). Also, strong correlations existed between the total recoveries (per million) and the total number of positive cases; total deaths (per million); median age; aged 70 older; GDP per capita; the number of hospital beds (per thousand); and HDI. The fitted regression models showed strong predictive powers (R-squared>99%) of the variances in the total number of COVID-19 cases (per million); total number of deaths (per million); and the total recoveries (per million).
The findings from this study suggest that patient-level characteristics such as ageing population (i.e., 65+), poverty, underlying co-morbidities-cardiovascular disease (e.g., hypertension), and diabetes through unhealthy behaviours like smoking as well as hospital care (i.e., beds per thousand) can help explain COVID-19 confirmed cases and mortality rates in Africa. Aside from these, other determinants (e.g., population density, the ability of detection, prevention and control) also affect COVID-19 prevalence, deaths and recoveries within African countries and sub-regions.
2019 年冠状病毒(COVID-19)使多个国家的卫生系统不堪重负,尤其是非洲地区的国家。然而,卫生系统与非洲国家 COVID-19 严重程度之间的关系尚未得到研究关注。在这项研究中,我们调查了非洲国家大流行的普遍程度与他们的全球卫生安全指数(GHSI)得分之间的关系。
该研究包括五个地区的 54 个国家,即西部(16 个);东部(18 个);中部(8 个);北部(7 个)和南部(5 个)非洲。本研究的结局变量为每百万例确诊的 COVID-19 病例总数;每百万例总康复数;以及每百万例总死亡数。对数据进行 Spearman 秩相关分析(Spearman rho),以确定每个预测变量与结局变量之间的单调关系。与结局变量呈单调关系的预测变量用于使用多元回归预测各自的结局变量。统计分析在显著性水平为 0.05 时进行。
我们的结果表明,每百万例 COVID-19 病例总数(rs>0.5)与中位年龄;65 岁以上;70 岁以上;人均国内生产总值;每千名人口的医院床位数;人类发展指数(HDI);康复人数(每百万例);以及国家的整体风险环境密切相关。所有这些因素,包括国家改善国家能力的承诺,都与每百万例总死亡人数有关。此外,每百万例总康复数与阳性病例总数、每百万例总死亡数、中位年龄、70 岁以上、人均国内生产总值、每千名人口的医院床位数和 HDI 之间存在很强的相关性。拟合回归模型对每百万例 COVID-19 病例总数(rs>0.5)、每百万例总死亡数和每百万例总康复数的方差具有很强的预测能力(R 平方>99%)。
本研究结果表明,人口统计学特征(如老龄化人口(即 65 岁以上)、贫困、潜在的合并症——心血管疾病(如高血压)和糖尿病)以及不健康行为(如吸烟)和医院护理(即每千名床位)等因素,都可以解释非洲的 COVID-19 确诊病例和死亡率。除此之外,其他决定因素(如人口密度、检测能力、预防和控制能力)也会影响非洲国家和次区域的 COVID-19 流行程度、死亡人数和康复人数。