Babaei Navid, Molaei Tina, Belyad Saeid, Hekmatfar Somayeh
Dental Students, Student Committee of Research, Faculty of Dentistry, Ardabil University of Medical Sciences, Ardabil, Iran.
Nursing and Midwifery Care Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Dent Res J (Isfahan). 2021 Feb 23;18:7. eCollection 2021.
Various iron drops are prescribed to children to prevent iron-deficiency anemia. The current study aimed to evaluate and compare the physicochemical profile of iron drops and the effect of these medicines on the color of primary teeth.
On the commencement of this experimental study, the pH and viscosity of five types of iron drops were measured. For the purpose of the current study, sixty healthy anterior deciduous teeth were provided; thereafter, they were assigned to five groups and then exposed to iron drops. The color and color difference of each specimen were measured by VİTA Easyshade Compact after 2 weeks. The amount of absorbed iron was determined by atomic absorption. The data were analyzed using two-way ANOVA and Tukey's test ( < 0.05).
As evidenced by the obtained results, all medications demonstrated acidic pH and discoloration. The viscosity values of iron drops were reported to be within the range of 2.07-33.58 cP. Based on the results of Pearson's correlation coefficient test, discoloration showed a correlation with pH and atomic absorption ( < 0.05).
Analyzed iron drops displayed low pH and discoloration higher than 3.3 which can be easily distinguished with naked eyes. Medicine labels should include warning statements on the feasibility of dental discoloration and erosion.
给儿童开各种铁滴剂以预防缺铁性贫血。本研究旨在评估和比较铁滴剂的物理化学特性以及这些药物对乳牙颜色的影响。
在本实验研究开始时，测量了五种铁滴剂的pH值和粘度。为了本研究的目的，提供了60颗健康的乳前牙；此后，将它们分为五组，然后暴露于铁滴剂中。两周后，使用VITA Easyshade Compact测量每个样本的颜色和色差。通过原子吸收法测定铁的吸收量。使用双向方差分析和Tukey检验（<0.05）对数据进行分析。
所得结果表明，所有药物均显示酸性pH值且会导致牙齿变色。据报道，铁滴剂的粘度值在2.07-33.58厘泊范围内。根据Pearson相关系数检验结果，牙齿变色与pH值和原子吸收呈相关性（<0.05）。
分析的铁滴剂显示出低pH值且变色程度高于3.3，肉眼可轻松辨别。药品标签应包括关于牙齿变色和腐蚀可能性的警示声明。
