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利雅得一家三级护理中心的藏毛窦疾病复发情况。

Pilonidal sinus disease recurrence at a tertiary care center in Riyadh.

机构信息

From the Department of Surgery, King Abdulaziz Medical City, Riyadh, Saudi Arabia.

From the College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.

出版信息

Ann Saudi Med. 2021 May-Jun;41(3):179-185. doi: 10.5144/0256-4947.2021.179. Epub 2021 Jun 1.

DOI:10.5144/0256-4947.2021.179
PMID:34085545
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8176377/
Abstract

BACKGROUND

Pilonidal sinus disease (PSD) is a chronic inflammatory disease of the sacrococcygeal area. Pilonidal sinus recurrence is a matter of concern to both patients and healthcare providers.

OBJECTIVES

Estimate the rate of PSD recurrence in our center and identify any risk factors contributing to disease recurrence.

DESIGN

Retrospective.

SETTING

Tertiary care center in Riyadh.

PATIENTS AND METHODS

All patients who underwent surgery for primary or recurrent pilonidal sinus between 1 January 2016 to 30 June 2019 were included to allow for at least 1-year of follow-up at the time of data collection.

MAIN OUTCOME MEASURE

Recurrence rate of PSD and risk factors for recurrence.

SAMPLE SIZE AND CHARACTERISTICS

369 patients: 329 males (89.2%) and 40 (10.8%) females. Median (interquartile range) age was 21 (18-26) years.

RESULTS

Of the 369 included patients, recurrence was identified in 84 (22.8%) cases [95% confidence interval (CI) 18.6-27.4], and the mean timing of recurrence was 1.8 (1.6) years after the primary surgery. In a multivariate logistic regression analysis, increased age and post-operative seroma fluid discharge were independent risk factors for recurrence. In contrast, preoperative antibiotic prophylaxis and postoperative hair removal were effective in reducing recurrence. Type of surgery closure had no effect on recurrence, yet primary closure was associated with early onset of recurrence compared to secondary closure (=.02).

CONCLUSION

Our findings on the factors associated with recurrence of PSD are consistent with many reports in the literature. Reported prevalence estimates vary widely.

LIMITATION

Single center, small sample size, retrospective.

CONFLICT OF INTEREST

None.

摘要

背景

藏毛窦疾病(PSD)是一种发生在尾骶区的慢性炎症性疾病。藏毛窦复发是患者和医疗保健提供者都关心的问题。

目的

估计我们中心 PSD 的复发率,并确定导致疾病复发的任何危险因素。

设计

回顾性研究。

设置

利雅得的一家三级保健中心。

患者和方法

所有在 2016 年 1 月 1 日至 2019 年 6 月 30 日期间接受原发性或复发性藏毛窦手术的患者均被纳入研究,以便在数据收集时至少有 1 年的随访。

主要观察指标

PSD 的复发率和复发的危险因素。

样本量和特征

369 例患者:329 例男性(89.2%)和 40 例女性(10.8%)。中位(四分位间距)年龄为 21(18-26)岁。

结果

在纳入的 369 例患者中,84 例(22.8%)患者复发[95%置信区间(CI)为 18.6-27.4%],平均复发时间为初次手术后 1.8(1.6)年。在多变量逻辑回归分析中,年龄增加和术后血清肿液排出是复发的独立危险因素。相比之下,术前抗生素预防和术后毛发清除可有效降低复发率。手术缝合类型对复发无影响,但与二期缝合相比,一期缝合与复发的早期发生有关(=0.02)。

结论

我们关于 PSD 复发相关因素的发现与文献中的许多报道一致。报道的患病率估计值差异很大。

局限性

单中心、小样本量、回顾性研究。

利益冲突

无。

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Sci Rep. 2020 Aug 13;10(1):13720. doi: 10.1038/s41598-020-70641-7.
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Risk factors of pilonidal sinus disease in preparatory school students; a case control study.预科学生藏毛窦疾病的危险因素;一项病例对照研究。
Ann Med Surg (Lond). 2020 Jul 15;57:46-48. doi: 10.1016/j.amsu.2020.07.016. eCollection 2020 Sep.
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Laser depilation as adjuvant therapy in prevention of recurrence of pilonidal sinus disease: initial experience of a district general hospital in the UK.激光脱毛作为辅助治疗预防藏毛窦疾病复发:英国一家区综合医院的初步经验
Ann R Coll Surg Engl. 2020 Nov;102(9):685-688. doi: 10.1308/rcsann.2020.0069. Epub 2020 Apr 17.
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Sci Rep. 2019 Oct 22;9(1):15111. doi: 10.1038/s41598-019-51159-z.
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