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巴西圣保罗市在 COVID-19 大流行期间因特定死因导致的超额死亡率。

Excess mortality by specific causes of deaths in the city of São Paulo, Brazil, during the COVID-19 pandemic.

机构信息

Group of Epidemiology and Statistics on Cancer, AC Camargo Cancer Center, São Paulo, SP, Brazil.

Intensive Care Unit, AC Camargo Cancer Center, São Paulo, SP, Brazil.

出版信息

PLoS One. 2021 Jun 7;16(6):e0252238. doi: 10.1371/journal.pone.0252238. eCollection 2021.

Abstract

BACKGROUND

To investigate the excess of deaths by specific causes, in the first half of 2020 in the city of São Paulo-Brazil, during the COVID-19 pandemic.

METHODS

Ecological study conducted from 01/01 to 06/30 of 2019 and 2020. Population and mortality data were obtained from DATASUS. The standardized mortality ratio (SMR) by age was calculated by comparing the standardized mortality rate in 2020 to that of 2019, for overall and specific mortality. The ratio between the standardized mortality rate due to COVID-19 in men as compared to women was calculated for 2020. Crude mortality rates were standardized using the direct method.

RESULTS

COVID-19 was responsible for 94.4% of the excess deaths in São Paulo. In 2020 there was an increase in overall mortality observed among both men (SMR 1.3, 95% CI 1.17-1.42) and women (SMR 1.2, 95% CI 1.06-1.36) as well as a towards reduced mortality for all cancers. Mortality due to COVID-19 was twice as high for men as for women (SMR 2.1, 95% CI 1.67-2.59). There was an excess of deaths observed in men above 45 years of age, and in women from the age group of 60 to 79 years.

CONCLUSION

There was an increase in overall mortality during the first six months of 2020 in São Paulo, which seems to be related to the COVID-19 pandemic. Chronic health conditions, such as cancer and other non-communicable diseases, should not be disregarded.

摘要

背景

在 2020 年 COVID-19 大流行期间,调查巴西圣保罗市 2020 年上半年特定原因导致的超额死亡人数。

方法

这是一项在 2019 年和 2020 年 1 月 1 日至 6 月 30 日进行的生态研究。人口和死亡率数据来自 DATASUS。通过比较 2020 年和 2019 年的标准化死亡率,计算出按年龄划分的标准化死亡率比值(SMR),用于总体和特定死亡率。计算了 2020 年男性与女性因 COVID-19 导致的标准化死亡率比值。使用直接法对粗死亡率进行标准化。

结果

COVID-19 是导致圣保罗超额死亡的 94.4%的原因。2020 年,男性(SMR 1.3,95%CI 1.17-1.42)和女性(SMR 1.2,95%CI 1.06-1.36)的总死亡率均有所上升,所有癌症的死亡率均有所下降。男性因 COVID-19 导致的死亡率是女性的两倍(SMR 2.1,95%CI 1.67-2.59)。45 岁以上男性和 60-79 岁女性的死亡人数均出现超额。

结论

2020 年前六个月,圣保罗的总死亡率有所上升,这似乎与 COVID-19 大流行有关。不应忽视癌症和其他非传染性疾病等慢性健康状况。

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