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[多巴胺对乳腺癌患者抗肿瘤免疫的影响]

[Effect of dopamine on the antitumor immunity of patients with breast cancer].

作者信息

Kharkevich D D

出版信息

Farmakol Toksikol. 1988 May-Jun;51(3):86-9.

PMID:3410039
Abstract

The effect of dopamine in the test of lymphocyte adhesion inhibition in vitro was studied in patients with early (I-IIA) and advanced (IIIB-IV) stages of breast cancer (BC). It was shown that the stimulating effect of dopamine revealed at concentrations of 10(-7)-10(-5) M was blocked by haloperidol (10(-6) M). During a comparative study of dopamine effect at the early and advanced stages of BC it was found that sensitivity of lymphocytes to the stimulating effect of dopamine at the advanced stages of BS was significantly lower as compared to that at the early stages.

摘要

研究了多巴胺在体外淋巴细胞黏附抑制试验中对早期(I-IIA期)和晚期(IIIB-IV期)乳腺癌(BC)患者的作用。结果表明,浓度为10^(-7)-10^(-5) M的多巴胺的刺激作用被氟哌啶醇(10^(-6) M)阻断。在对BC早期和晚期多巴胺作用的比较研究中发现,与早期相比,BS晚期淋巴细胞对多巴胺刺激作用的敏感性显著降低。

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[Effect of dopamine on the antitumor immunity of patients with breast cancer].[多巴胺对乳腺癌患者抗肿瘤免疫的影响]
Farmakol Toksikol. 1988 May-Jun;51(3):86-9.
2
[Effect of stimulation of dopamine and histamine receptors on spontaneous lymphocyte adhesion in vitro].[多巴胺和组胺受体刺激对体外自发淋巴细胞黏附的影响]
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[Histamine-receptor sensitivity of lymphocytes in patients with early and advanced stage breast cancer].[早期和晚期乳腺癌患者淋巴细胞的组胺受体敏感性]
Eksp Onkol. 1988;10(1):27-30.
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In vitro exposure to paclitaxel modulates integrin expression by human T lymphocytes and inhibits T cell adhesion to breast carcinoma cells.体外暴露于紫杉醇可调节人T淋巴细胞的整合素表达,并抑制T细胞与乳腺癌细胞的黏附。
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