德国骨髓炎的负担有多重？2008 年至 2018 年住院数据的分析。
What is the burden of osteomyelitis in Germany? An analysis of inpatient data from 2008 through 2018.
机构信息
Department for Trauma Surgery, University Medical Center Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Germany.
Department for Psychosomatic Medicine, University Medical Center Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg, Germany.
出版信息
BMC Infect Dis. 2021 Jun 10;21(1):550. doi: 10.1186/s12879-021-06274-6.
BACKGROUND
The epidemiology of osteomyelitis in Germany is unknown, which makes it difficult to estimate future demands. Therefore, we aimed to analyse how the numbers of cases have developed over the last decade as a function of osteomyelitis subtype, age group, gender, and anatomical localization.
METHODS
Osteomyelitis rates were quantified based on annual ICD-10 diagnosis codes from German medical institutions between 2008 through 2018, provided by the Federal Statistical Office of Germany (Destatis).
RESULTS
Overall osteomyelitis prevalence increased by 10.44% from 15.5 to 16.7 cases per 100,000 inhabitants between 2008 through 2018. Out of 11,340 cases in 2018, 47.6% were diagnosed as chronic, 33.2% as acute and 19.2% as unspecified osteomyelitis. Men were often affected than women with 63.4% of all cases compared to 36.6%. The largest proportion of patients comprised the age group 60-69 years (22.1%), followed by 70-79 years (21.7%). A trend towards more osteomyelitis diagnoses in older patients was observed. Lower extremities were most frequently infected with 73.8% of all cases in 2018 (+ 10.8% change).
CONCLUSIONS
Osteomyelitis remains a serious problem for orthopedic and trauma surgery. Prevention methods and interdisciplinary approaches are strongly required.
背景
德国骨髓炎的流行病学情况未知，这使得难以预估未来的需求。因此，我们旨在分析过去十年中骨髓炎病例数量的发展情况，以及骨髓炎的亚型、年龄组、性别和解剖部位等因素。
方法
基于德国联邦统计局（Destatis）提供的 2008 年至 2018 年期间德国医疗机构的 ICD-10 诊断代码，我们量化了骨髓炎的发病率。
结果
2008 年至 2018 年间，总体骨髓炎患病率从每 10 万人中有 15.5 例增加到 16.7 例，增长了 10.44%。2018 年的 11340 例病例中，47.6%被诊断为慢性骨髓炎，33.2%为急性骨髓炎，19.2%为未特指骨髓炎。男性比女性更容易受到影响，所有病例中男性占 63.4%，女性占 36.6%。年龄组 60-69 岁的患者比例最大（22.1%），其次是 70-79 岁（21.7%）。观察到患者中年龄较大的人有更多的骨髓炎诊断趋势。2018 年，下肢是最常受感染的部位，占所有病例的 73.8%（变化率为+10.8%）。
结论
骨髓炎仍然是骨科和创伤外科的一个严重问题。需要采取预防措施和采取多学科方法。
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