Sharma Lakshika, Dhiman Mamta, Singh Abhijeet, Sharma M M
Department of Biosciences, Manipal University Jaipur, Jaipur, India.
Front Mol Biosci. 2021 May 28;8:655584. doi: 10.3389/fmolb.2021.655584. eCollection 2021.
The present review focuses on a dreaded vector-mediated leishmaniasis, with the existing therapeutic approaches including a variety of drugs along with their limitations, the treatment with natural compounds, and different types of metal/metal oxide nanoparticles (NPs). As evidenced, various metallic NPs, comprising silver, silver oxide, gold, zinc oxide, titanium, lead oxide, , played a curative role to treat leishmaniasis, are also presented. Keeping in view the advance success of vaccines against the prevalent dreaded diseases in the past and the present scenario, efforts are also being made to develop vaccines based on these NP formulations.
本综述聚焦于一种可怕的媒介传播利什曼病，现有治疗方法包括多种药物及其局限性、天然化合物治疗以及不同类型的金属/金属氧化物纳米颗粒（NPs）。事实证明，包括银、氧化银、金、氧化锌、钛、氧化铅等在内的各种金属NPs在治疗利什曼病中发挥了治疗作用，本文也有介绍。鉴于过去和当前针对常见可怕疾病的疫苗取得的巨大成功，人们也在努力研发基于这些NP制剂的疫苗。
