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基于 MRI 体素空间重建的人类皮质中枢形态学和功能学的骨髓和细胞构筑微结构图谱

Myelo- and cytoarchitectonic microstructural and functional human cortical atlases reconstructed in common MRI space.

机构信息

Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam Neuroscience, Amsterdam, the Netherlands.

Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam Neuroscience, Amsterdam, the Netherlands.

出版信息

Neuroimage. 2021 Oct 1;239:118274. doi: 10.1016/j.neuroimage.2021.118274. Epub 2021 Jun 17.

DOI:10.1016/j.neuroimage.2021.118274
PMID:34146709
Abstract

The parcellation of the brain's cortical surface into anatomically and/or functionally distinct areas is a topic of ongoing investigation and interest. We provide digital versions of six classical human brain atlases in common MRI space. The cortical atlases represent a range of modalities, including cyto- and myeloarchitecture (Campbell, Smith, Brodmann and Von Economo), myelogenesis (Flechsig), and mappings of symptomatic information in relation to the spatial location of brain lesions (Kleist). Digital reconstructions of these important cortical atlases widen the range of modalities for which cortex-wide imaging atlases are currently available and offer the opportunity to compare and combine microstructural and lesion-based functional atlases with in-vivo imaging-based atlases.

摘要

大脑皮质表面的分区是一个正在进行的研究和关注的课题,将其划分为解剖学和/或功能上不同的区域。我们提供了六个常见 MRI 空间中经典的人类大脑图谱的数字版本。皮质图谱代表了一系列模态,包括细胞和髓鞘结构(坎贝尔、史密斯、布罗德曼和冯·埃克诺莫)、髓鞘发生(弗莱希希),以及与大脑病变空间位置相关的症状信息映射(克莱斯特)。这些重要皮质图谱的数字重建拓宽了目前可用的皮质全脑成像图谱的模态范围,并提供了比较和组合基于微观结构和病变的功能图谱与基于体内成像的图谱的机会。

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