Telethon Kids Institute, Northern Entrance, Perth Children's Hospital, 15 Hospital Avenue, Nedlands WA 6009, PO Box 855, West Perth, WA 6872, Australia; Edith Cowan University, 270 Joondalup Dr, Joondalup, WA 6027, Australia.
Telethon Kids Institute, Northern Entrance, Perth Children's Hospital, 15 Hospital Avenue, Nedlands WA 6009, PO Box 855, West Perth, WA 6872, Australia; The University of Western Australia, 35 Stirling Hwy, Crawley, WA 6009, Australia; Joondalup Health Campus, Suite 210 Specialist Centre, 60 Shenton Avenue, Joondalup WA 6027, Australia; Edith Cowan University, 270 Joondalup Dr, Joondalup, WA 6027, Australia.
Paediatr Respir Rev. 2021 Dec;40:3-9. doi: 10.1016/j.prrv.2021.05.005. Epub 2021 May 26.
With well-established evidence that early life conditions have a profound influence on lifespan and health-span, new interventional birth cohorts are examining ways to optimise health potential of individuals and communities. These are aimed at going beyond preventing disease, to the conditions that facilitate flourishing from an early age. Covering diverse domains, local community projects, such as The ORIGINS Project, are taking a broader approach to the protective and buffering factors that enhance resilience and reduce allostatic load, such as building nature relatedness, interpersonal relationships, mindfulness, and positive emotions. Such cohorts aim to address how 'upstream' approaches will have flow on effects to the 'historical' risk targets (such as poor nutrition, physical inactivity, and stress) by influencing these core behaviours through better relationships with self, community, and the environment. In addition to scientific pursuit, interventional cohorts can contribute to solutions ineverycommunity - nourishing individuals and communities towards positive change.
有充分的证据表明，生命早期的条件对寿命和健康寿命有深远的影响，新的干预性出生队列正在研究如何优化个体和社区的健康潜力。这些队列的目的不仅仅是预防疾病，还要关注那些从早期就促进繁荣的条件。涵盖了不同的领域，如 ORIGINS 项目等当地社区项目，正在采取更广泛的方法来研究增强适应力和减少压力的保护和缓冲因素，例如建立与自然的联系、人际关系、正念和积极情绪。这些队列旨在通过改善与自我、社区和环境的关系，通过更好地控制这些核心行为，来解决“上游”方法将如何对“历史”风险目标（如营养不良、身体活动不足和压力）产生影响。除了科学追求，干预性队列还可以为每个社区的解决方案做出贡献——滋养个人和社区，促进积极的变化。
