从禾谷镰刀菌MRC 1125玉米培养物中分离和鉴定单端孢霉烯毒素
Isolation and characterization of trichothecin from corn cultures of Fusarium graminearum MRC 1125.
作者信息
Combrinck S, Gelderblom W C, Spies H S, Burger B V, Thiel P G, Marasas W F
机构信息
Research Institute for Nutritional Diseases, South African Medical Research Council, Tygerberg.
出版信息
Appl Environ Microbiol. 1988 Jul;54(7):1700-2. doi: 10.1128/aem.54.7.1700-1702.1988.
Abstract
Trichothecin was isolated and purified from corn cultures of a toxic strain of Fusarium graminearum. This strain, designated MRC 1125, was obtained from corn in southern Africa. The brine shrimp toxicity assay was used throughout the isolation procedure to monitor the toxicity of the fractions. The compound was characterized by detailed 1H (500-MHz) and 13C (125-MHz) nuclear magnetic resonance spectroscopy and mass spectrometry. This is the first report of the production of trichothecin by a Fusarium species.
摘要
从禾谷镰刀菌有毒菌株的玉米培养物中分离并纯化了单端孢霉烯毒素。该菌株命名为MRC 1125，从非洲南部的玉米中获得。在整个分离过程中使用卤虫毒性试验来监测各组分的毒性。通过详细的1H（500兆赫兹）和13C（125兆赫兹）核磁共振光谱以及质谱对该化合物进行了表征。这是关于镰刀菌属产生单端孢霉烯毒素的首次报道。
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