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来自镰刀菌感染玉米的拒食和催吐原理的共同特性。

Co-identity of the refusal and emetic principle from Fusarium-infected corn.

作者信息

Vesonder R F, Ciegler A, Jensen A H, Rohwedder W K, Weisleder D

出版信息

Appl Environ Microbiol. 1976 Feb;31(2):280-5. doi: 10.1128/aem.31.2.280-285.1976.

DOI:10.1128/aem.31.2.280-285.1976
PMID:999277
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC169760/
Abstract

The structure of vomitoxin isolated from Fusarium-contaminated corn was proved to be 3,7,15-trihydroxy-12,13-epoxytrichothec-9-en-8-one. This same toxin is responsible for the "refusal phenomenon" exhibited by swine fed contaminated corn. In addition, two new substances believed to be trichothecenes were isolated from naturally infected corn. Vomitoxin was also isolated from rice inoculated with F. graminearium NRRL 5883.

摘要

从受镰刀菌污染的玉米中分离出的呕吐毒素的结构被证明是3,7,15-三羟基-12,13-环氧单端孢霉烯-9-烯-8-酮。这种毒素同样导致了喂食受污染玉米的猪出现“拒食现象”。此外,从自然感染的玉米中分离出了两种被认为是单端孢霉烯族毒素的新物质。呕吐毒素也从接种了禾谷镰刀菌NRRL 5883的水稻中分离出来。

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Co-identity of the refusal and emetic principle from Fusarium-infected corn.来自镰刀菌感染玉米的拒食和催吐原理的共同特性。
Appl Environ Microbiol. 1976 Feb;31(2):280-5. doi: 10.1128/aem.31.2.280-285.1976.
2
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本文引用的文献

1
Toxicological approaches to the metabolites of Fusaria. 3. Acute toxicity of fusarenon-X.镰刀菌代谢产物的毒理学研究方法。3. 镰刀菌烯酮-X的急性毒性
Jpn J Exp Med. 1971 Dec;41(6):521-39.
2
Isolation of the emetic principle from Fusarium-infected corn.从受镰刀菌感染的玉米中分离催吐毒素。
Appl Microbiol. 1973 Dec;26(6):1008-10. doi: 10.1128/am.26.6.1008-1010.1973.
3
T-2 toxin as an emetic factor in moldy corn.T-2毒素作为霉变玉米中的一种催吐因子。
Appl Microbiol. 1973 Oct;26(4):540-3. doi: 10.1128/am.26.4.540-543.1973.
4
Toxicological approaches to the metabolites of Fusaria. VI. Vomiting factor from moldy corn infected with Fusarium spp.镰刀菌代谢产物的毒理学研究方法。VI. 感染镰刀菌属的发霉玉米中的呕吐因子
Jpn J Exp Med. 1974 Feb;44(1):123-7.
5
New metabolic products of Fusarium culmorum: toxic trichothec-9-en-8-ones and 2-acetylquinazolin-4(3h)-one.禾谷镰刀菌的新代谢产物:有毒的单端孢霉烯-9-烯-8-酮和2-乙酰基喹唑啉-4(3H)-酮。
J Chem Soc Perkin 1. 1974;0(14):1691-3.