Department of Clinical Internal, Anesthesiologic and Cardiovascular Sciences, Sapienza University of Rome, Roma, Lazio, Italy
Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Sapienza University of Rome, Roma, Italy
Thorax. 2021 Jun;76(6):618-620. doi: 10.1136/thoraxjnl-2020-215900. Epub 2021 Apr 19.
Tobacco habit still represents the leading preventable cause of morbidity and mortality worldwide. Heat-not-burn cigarettes (HNBCs) are considered as an alternative to traditional combustion cigarettes (TCCs) due to the lack of combustion and the absence of combustion-related specific toxicants. The aim of this observational study was to assess the effect of HNBC on endothelial function, oxidative stress and platelet activation in chronic adult TCC smokers and HNBC users. The results showed that both HNBC and TCC display an adverse phenotype in terms of endothelial function, oxidative stress and platelet activation. Future randomised studies are strongly warranted to confirm these data.
吸烟习惯仍然是全球可预防的发病率和死亡率的主要原因。由于缺乏燃烧和不存在与燃烧相关的特定毒物，加热不燃烧卷烟（HNBC）被认为是传统卷烟（TCC）的替代品。本观察性研究旨在评估 HNBC 对慢性成年 TCC 吸烟者和 HNBC 用户的内皮功能、氧化应激和血小板激活的影响。结果表明，HNBC 和 TCC 在内皮功能、氧化应激和血小板激活方面均表现出不良表型。强烈需要进行未来的随机研究来证实这些数据。
