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使用维生素C作为抗炎剂治疗持续性牙龈炎症的中胚层疗法:病例系列

Mesotherapy using Vitamin C as an anti-inflammatory agent in persistent gingival inflammation: A case series.

作者信息

Brahmavar Bhavya, Khan Safiya Fatima, Khan Asim Mustafa

机构信息

Department of Periodontology, Faculty of Dental Sciences, Ramaiah University of Applied Sciences, Bengaluru, Karnataka, India.

Department of Biomedical Dental Science, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

出版信息

J Indian Soc Periodontol. 2021 May-Jun;25(3):203-206. doi: 10.4103/jisp.jisp_443_20. Epub 2021 May 3.

DOI:10.4103/jisp.jisp_443_20
PMID:34158686
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8177174/
Abstract

BACKGROUND

Mesotherapy is a minimally invasive procedure which involves local intradermal therapy (LIT) with biologically active substances given in minor quantities to the area of pathology. Vitamin C is an important antioxidant agent which can modulate the attenuation of inflammatory process and enhance tissue repair.

AIM

The aim of this study was to investigate the efficacy of local injections of Vitamin C for treating persisting inflammation of the gingiva.

MATERIALS AND METHODS

After phase I therapy was completed, five patients with persisting chronic inflammation of the gingiva were injected with the same dosages of Vitamin C into the gingival tissues. Patients were evaluated each week for resolution of gingival inflammation.

RESULTS

Clinical observation showed a significant improvement in inflammation of the injected sites during recall appointments.

CONCLUSIONS

LIT with Vitamin C has a synergistic interaction along with scaling and root planing in the treatment of persistent gingival inflammation.

摘要

背景

中胚层疗法是一种微创手术,涉及局部皮内治疗(LIT),将少量生物活性物质注射到病变区域。维生素C是一种重要的抗氧化剂,可调节炎症过程的减轻并促进组织修复。

目的

本研究的目的是调查局部注射维生素C治疗牙龈持续炎症的疗效。

材料和方法

在第一阶段治疗完成后,对五名牙龈持续慢性炎症患者的牙龈组织注射相同剂量的维生素C。每周对患者进行评估,以观察牙龈炎症的消退情况。

结果

临床观察显示,在复诊时注射部位的炎症有显著改善。

结论

维生素C局部皮内治疗在治疗持续性牙龈炎症方面与龈上洁治和根面平整具有协同作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf2f/8177174/9a822aef31af/JISP-25-203-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf2f/8177174/b60b300a320e/JISP-25-203-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf2f/8177174/b322baa8f3d6/JISP-25-203-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf2f/8177174/86c20793cc62/JISP-25-203-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf2f/8177174/b5b0e695492a/JISP-25-203-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf2f/8177174/9a822aef31af/JISP-25-203-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf2f/8177174/b60b300a320e/JISP-25-203-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf2f/8177174/b322baa8f3d6/JISP-25-203-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf2f/8177174/86c20793cc62/JISP-25-203-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf2f/8177174/b5b0e695492a/JISP-25-203-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf2f/8177174/9a822aef31af/JISP-25-203-g005.jpg

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Mediators Inflamm. 2014;2014:173403. doi: 10.1155/2014/173403. Epub 2014 Sep 9.
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Effects of an ascorbic acid-derivative dentifrice in patients with gingivitis: a double-masked, randomized, controlled clinical trial.
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Vitamin C mesotherapy versus diode laser for the esthetic management of physiologic gingival hyperpigmentation: a randomized clinical trial.维生素 C 中胚层疗法与二极管激光治疗生理性牙龈色素沉着的美学效果:一项随机临床试验。
BMC Oral Health. 2023 Nov 21;23(1):899. doi: 10.1186/s12903-023-03614-7.
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