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睾丸癌机器人腹膜后淋巴结清扫术的治疗效果及适应证拓展

Outcomes and expanding indications for robotic retroperitoneal lymph node dissection for testicular cancer.

作者信息

Yang Hailiu, Obiora Daisy, Tomaszewski Jeffrey J

机构信息

Division of Urology, Department of Surgery, Cooper University Hospital, Camden, NJ, USA.

Division of Urology, Department of Surgery, MD Anderson Cancer Center at Cooper, Cooper Medical School of Rowan University, Camden, NJ, USA.

出版信息

Transl Androl Urol. 2021 May;10(5):2188-2194. doi: 10.21037/tau.2020.03.14.

DOI:10.21037/tau.2020.03.14
PMID:34159101
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8185654/
Abstract

Treatment of testicular cancer has made significant progress in the past decades in terms of reduction of treatment-associated morbidity and preventing over-treatment. At the forefront of this progression is utilization of the da Vinci robot to perform retroperitoneal lymph node dissections (RPLNDs) via a minimally invasive approach. The robot offers multiple potential advantages such as smaller incisions, improved 3D visualization, more precise dissection, and faster convalescence, leading to its increased usage the past several years. In this chapter, we summarize the recent progress made in robotic surgery for testicular cancer and its potential in the future. Promising preliminary data has also renewed interest in defining the role of primary RPLND in patients with seminoma, potentially sparing patients of the harmful long-term radiation and cisplatin-based chemotherapy. SEMS and PRIMETEST trials are ongoing trials that will provide significant insight into this area and potentially expand the role of robotic RPLND.

摘要

在过去几十年里,睾丸癌的治疗在降低治疗相关发病率和避免过度治疗方面取得了显著进展。这一进展的前沿是利用达芬奇机器人通过微创方法进行腹膜后淋巴结清扫术(RPLND)。该机器人具有多个潜在优势,如切口更小、三维可视化改善、解剖更精确以及恢复更快,导致其在过去几年中的使用增加。在本章中,我们总结了机器人手术治疗睾丸癌的最新进展及其未来潜力。有前景的初步数据也重新引发了人们对确定原发性RPLND在精原细胞瘤患者中的作用的兴趣,这可能使患者免受长期有害放疗和顺铂化疗之苦。SEMS和PRIMETEST试验正在进行中,将为该领域提供重要见解,并可能扩大机器人RPLND的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f9d/8185654/30827a87db61/tau-10-05-2188-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f9d/8185654/72449d270278/tau-10-05-2188-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f9d/8185654/30827a87db61/tau-10-05-2188-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f9d/8185654/72449d270278/tau-10-05-2188-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f9d/8185654/30827a87db61/tau-10-05-2188-f2.jpg

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本文引用的文献

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J Robot Surg. 2019 Dec;13(6):747-756. doi: 10.1007/s11701-018-00903-0. Epub 2019 Jan 17.
2
Robot-assisted post-chemotherapy retroperitoneal lymph node dissection in germ cell tumor: is the single-docking with lateral approach relevant?机器人辅助化疗后腹膜后淋巴结清扫术在生殖细胞肿瘤中的应用:单 docking 与侧入路相关吗?
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Robot-assisted retroperitoneal lymph node dissection: Feasibility and outcome in postchemotherapy residual mass in testicular cancer.
机器人辅助腹膜后淋巴结清扫术:睾丸癌化疗后残留肿块的可行性及结果
Indian J Urol. 2017 Oct-Dec;33(4):304-309. doi: 10.4103/iju.IJU_8_17.
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Post-chemotherapy robotic bilateral retroperitoneal lymph node dissection using a novel single-dock technique.化疗后采用新型单对接技术的机器人双侧腹膜后淋巴结清扫术。
J Robot Surg. 2016 Dec;10(4):353-356. doi: 10.1007/s11701-016-0622-8. Epub 2016 Jul 26.
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Safety and Early Oncologic Effectiveness of Primary Robotic Retroperitoneal Lymph Node Dissection for Nonseminomatous Germ Cell Testicular Cancer.机器人辅助腹膜后淋巴结清扫术治疗非精原细胞瘤性生殖细胞睾丸癌的安全性和早期肿瘤学效果。
Eur Urol. 2017 Mar;71(3):476-482. doi: 10.1016/j.eururo.2016.05.017. Epub 2016 May 24.
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