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机器人辅助腹膜后淋巴结清扫术:睾丸癌化疗后残留肿块的可行性及结果

Robot-assisted retroperitoneal lymph node dissection: Feasibility and outcome in postchemotherapy residual mass in testicular cancer.

作者信息

Singh Amitabh, Chatterjee Smaranjit, Bansal Prashant, Bansal Abhishek, Rawal Sudhir

机构信息

Department of Uro-oncology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, India.

出版信息

Indian J Urol. 2017 Oct-Dec;33(4):304-309. doi: 10.4103/iju.IJU_8_17.

DOI:10.4103/iju.IJU_8_17
PMID:29021655
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5635672/
Abstract

INTRODUCTION

We aimed to evaluate the surgical feasibility, complication, and oncological outcome of robot-assisted retroperitoneal lymph node dissection (RA-RPLND) in patients of testicular tumor with postchemotherapy residual retroperitoneal mass.

METHODS

A total of 13 patients underwent RA-RPLND between January 2012 and September 2016 at our institute. A study was started on December 2015, so data were collected retrospectively and prospectively regarding patient demography, tumor characteristics, surgical, pathological outcome, and oncological outcome.

RESULTS

RA-RPLND was successfully completed in all the 13 patients. Lateral approach was used in initial 12 patients with unilateral dissection in 11 patients and bilateral dissection after in 1 patient after repositioning in bilateral position. Supine robotic approach used in 1 patient. Median operative time was 200 min, median estimated blood loss was 120 ml, and median length of hospital stay was 4 days. The median yield of lymph node was 20. Three patients had positive lymph nodes, all had teratoma germ cell tumor. Ten patients had only necrosis in lymph nodes. After median follow-up 23 months (range 3-58 months), no systemic or retroperitoneal recurrence was found. Four patients developed chyle leak. One patient was managed conservatively with diet modification, one with intranodal lipiodol lymphangiography and two patients were managed surgically.

CONCLUSION

RA-RPLND is safe and feasible for postchemotherapy residual mass with accepted compilation rate, but larger studies are required to establish its diagnostic and therapeutic utility along with safety of the procedure.

摘要

引言

我们旨在评估机器人辅助腹膜后淋巴结清扫术(RA - RPLND)在化疗后残留腹膜后肿块的睾丸肿瘤患者中的手术可行性、并发症及肿瘤学结局。

方法

2012年1月至2016年9月期间,我院共有13例患者接受了RA - RPLND。该研究于2015年12月启动,因此回顾性和前瞻性收集了有关患者人口统计学、肿瘤特征、手术、病理结果及肿瘤学结局的数据。

结果

13例患者均成功完成RA - RPLND。最初的12例患者采用侧入路,其中11例为单侧清扫,1例在重新调整为双侧体位后进行了双侧清扫。1例患者采用仰卧位机器人入路。中位手术时间为200分钟,中位估计失血量为120毫升,中位住院时间为4天。淋巴结的中位收获量为20个。3例患者淋巴结阳性,均为畸胎瘤生殖细胞肿瘤。10例患者淋巴结仅出现坏死。中位随访23个月(范围3 - 58个月)后,未发现全身或腹膜后复发。4例患者出现乳糜漏。1例患者通过饮食调整进行保守治疗,1例进行了节点内碘油淋巴管造影,2例患者接受了手术治疗。

结论

RA - RPLND对于化疗后残留肿块是安全可行的,并发症发生率可接受,但需要更大规模的研究来确定其诊断和治疗效用以及该手术的安全性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ac6/5635672/19ec45606883/IJU-33-304-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ac6/5635672/1d545d8478a5/IJU-33-304-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ac6/5635672/155403c88dd8/IJU-33-304-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ac6/5635672/ed8e79dcc2b7/IJU-33-304-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ac6/5635672/19ec45606883/IJU-33-304-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ac6/5635672/1d545d8478a5/IJU-33-304-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ac6/5635672/155403c88dd8/IJU-33-304-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ac6/5635672/ed8e79dcc2b7/IJU-33-304-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ac6/5635672/19ec45606883/IJU-33-304-g006.jpg

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