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基于计算机深度学习的肺栓塞人工智能诊断初步研究

Preliminary study on artificial intelligence diagnosis of pulmonary embolism based on computer in-depth study.

作者信息

Li Xiang, Wang Xiang, Yang Xin, Lin Yi, Huang Zengfa

机构信息

The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Huazhong University of Science and Technology, College of Automation and Artificial Intelligence, Wuhan, China.

出版信息

Ann Transl Med. 2021 May;9(10):838. doi: 10.21037/atm-21-975.

Abstract

BACKGROUND

Objective to preliminarily verify the feasibility of AI intelligent diagnosis of pulmonary embolism by using a new artificial intelligence (AI) computer-aided diagnosis system (CAD) to localize and quantitatively diagnose pulmonary embolism in pulmonary artery CT angiography (CTA).

METHODS

Computed tomography angiography (CTA) data of 85 patients with PE in our hospital from January 2017 to May 2018 were retrospectively collected and randomly allocated to2 groups: computer depth learning group (n=43) and experimental group (n=42). For the training set (13,144 sheets) and the test set (313 sheets), the auxiliary diagnosis method was obtained and applied to the experimental group.

RESULTS

Among the participants, a good sensitivity of 90.9% and an average false positive of 2.0 were obtained by using the deep learning detection method proposed in this paper, and the detection rate was positively correlated with arterial grade.

CONCLUSIONS

The computer-aided diagnostic method proposed in this paper can effectively improve the detection rate of PE, especially for the detection of intra-arterial embolism above grade 3. However, because of the high misdetection rate, more in-depth learning datasets are needed for the detection of embolism below grade 3.

摘要

背景

目的通过使用一种新的人工智能(AI)计算机辅助诊断系统(CAD)对肺动脉CT血管造影(CTA)中的肺栓塞进行定位和定量诊断,初步验证AI智能诊断肺栓塞的可行性。

方法

回顾性收集我院2017年1月至2018年5月85例肺栓塞患者的计算机断层血管造影(CTA)数据,并随机分为两组:计算机深度学习组(n = 43)和实验组(n = 42)。对于训练集(13144张)和测试集(313张),获得辅助诊断方法并应用于实验组。

结果

在参与者中,使用本文提出的深度学习检测方法获得了90.9%的良好敏感性和2.0的平均假阳性率,且检测率与动脉分级呈正相关。

结论

本文提出的计算机辅助诊断方法可有效提高肺栓塞的检测率,尤其是对3级以上动脉内栓塞的检测。然而,由于误检率较高,对于3级以下栓塞的检测需要更多深入的学习数据集。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b64/8184458/1beacff7d020/atm-09-10-838-f1.jpg

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