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新冠肺炎疫情对不同抑郁史人群心理健康的影响:一项社区前瞻性队列数据的心理健康调查。

Impact of COVID-19 on mental health according to prior depression status: A mental health survey of community prospective cohort data.

机构信息

Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.

出版信息

J Psychosom Res. 2021 Sep;148:110552. doi: 10.1016/j.jpsychores.2021.110552. Epub 2021 Jun 18.

Abstract

OBJECTIVE

We aimed to investigate the mental health impact of COVID-19 on a demographically well-characterized population cohort by gender and previous depression status.

METHODS

Among people who participated in a community cohort study between 2013 and 2018 with previous depression measurement, a total of 1928 people without quarantine experience (680 men and 1249 women) were included after responding to an online survey in March 2020. In the 2020 survey, people were queried about daily needs supply, social support, risk perception, change during the COVID-19 pandemic, as well as mental health indices measuring loneliness, anxiety symptoms, post-traumatic stress disorder (PTSD), and depression. Separate analyses by gender were conducted to assess the association between COVID-19-related experiences and each mental health index, using multivariable logistic regressions with additional adjustment and stratification with pre-existing depression status.

RESULTS

We could not observe significant gender differences for depression, anxiety, PTSD, and loneliness at 55 days after the start of the COVID-19 outbreak. Most external support, including daily needs supply and social support, protected men and women from experiencing severe anxiety (for life supply, OR = 0.92 (95%CI 0.88-0.97) (men) and OR = 0.95 (95% CI 0.91-0.99) (women); for social support, OR = 0.92(both for men and women, p < 0.01)). The results were similar for depression and PTSD. External support showed a larger reduction in the likelihoods for anxiety and depression during the COVID-19 pandemic among people with pre-existing depression compared to previously healthy people, and it was more prominent in men.

CONCLUSION

COVID-19 significantly affected the mental health of both men and women in the early period of the pandemic. Having enough supply of daily needs and social support seems important, especially for people with previous depression.

摘要

目的

通过性别和既往抑郁状况,研究 COVID-19 对人口特征良好的人群队列的心理健康影响。

方法

在参加了 2013 年至 2018 年期间的社区队列研究且有既往抑郁测量的人群中,共有 1928 人未经历过隔离(680 名男性和 1249 名女性),他们在 2020 年 3 月回复了在线调查后被纳入研究。在 2020 年的调查中,询问了人们日常需求供应、社会支持、风险感知、COVID-19 大流行期间的变化,以及衡量孤独感、焦虑症状、创伤后应激障碍(PTSD)和抑郁的心理健康指标。通过多变量逻辑回归进行了单独的性别分析,并对 COVID-19 相关经历与每个心理健康指标之间的关联进行了调整和分层,纳入了既往抑郁状况。

结果

在 COVID-19 爆发开始后的 55 天,我们没有观察到抑郁、焦虑、PTSD 和孤独感方面存在显著的性别差异。大多数外部支持,包括日常需求供应和社会支持,使男性和女性免受严重焦虑的影响(对于生活供应,OR=0.92(95%CI 0.88-0.97)(男性)和 OR=0.95(95%CI 0.91-0.99)(女性);对于社会支持,OR=0.92(男性和女性都适用,p<0.01))。对于抑郁和 PTSD 也得到了类似的结果。与之前健康的人相比,外部支持在患有既往抑郁的人群中降低 COVID-19 期间焦虑和抑郁发生可能性的作用更大,并且在男性中更为明显。

结论

COVID-19 在大流行早期显著影响了男性和女性的心理健康。有足够的日常需求供应和社会支持似乎很重要,特别是对有既往抑郁的人而言。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/871c/8590509/570c7029256e/gr1_lrg.jpg

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