From the Hagey Laboratory for Pediatric Regenerative Medicine, Division of Plastic Surgery, Department of Surgery, Stanford University School of Medicine.
Plast Reconstr Surg. 2021 Jul 1;148(1):77-87. doi: 10.1097/PRS.0000000000008065.
Striae distensae, or stretch marks, are common linear lesions of atrophic skin characterized histologically by epidermal atrophy, absent rete ridges, and alterations in connective tissue architecture. Hormonal excess, mechanical stress, and genetic predisposition are all associated with striae distensae, but their exact pathogenesis remains unknown. Despite a multitude of options, no single treatment has yet proven effective. In this article, the authors describe an up-to-date overview of striae distensae in terms of their etiology, pathophysiology, and therapeutic options. Further research is required to better elucidate their pathophysiology and to develop targeted effective treatments.
妊娠纹，又称伸展纹，是一种常见的皮肤萎缩性线性病变，组织学上表现为表皮萎缩、网嵴缺失以及结缔组织结构改变。激素过多、机械应力和遗传易感性都与妊娠纹有关，但确切的发病机制尚不清楚。尽管有多种选择，但尚无单一治疗方法被证明有效。本文作者就妊娠纹的病因、发病机制和治疗方法进行了全面综述。进一步的研究需要更好地阐明其发病机制，并开发有针对性的有效治疗方法。
