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2011 - 2015年伊朗艾滋病病毒诊断的终生风险和年龄条件风险评估

Estimating the Lifetime and Age-Conditional Risk of an HIV Diagnosis in Iran, 2011-2015.

作者信息

Nasirian Maryam, Mahboobi Marzieh, Maracy Mohammad Reza

机构信息

Department of Biostatistic and Epidemiology, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran.

Center for Communicable Diseases Control, Ministry of Health and Medical Educationa, Tehran, Iran.

出版信息

Iran J Public Health. 2021 May;50(5):1048-1055. doi: 10.18502/ijph.v50i5.6122.

Abstract

BACKGROUND

According to the importance of infectious diseases, especially HIV, the purpose of this study was to estimate lifetime and age-conditional risks of HIV diagnosis in Iran.

METHODS

We used vital statistics, HIV surveillance and census data for 2011-2015 to calculate Age-specific HIV diagnosis and non-HIV death rates. These rates then converted to the probability of an HIV diagnosis considering the competing risk. Finally, the probabilities were applied to a hypothetical cohort of 10 million live births. The lifetime and age-conditional risk of HIV diagnosis in the total and general population of Iran were calculated by Dev Can software (version 6.7.4).

RESULTS

Lifetime risk was 0.084% (95% CI: 0.081-0.088) or one in 1183 for females and 0.21% (95% CI: 0.201-0.211) or one in 483 for males in the total population. In the general population lifetime risk for men was 0.069% (95% CI: 0.066-0.072) or 1 in 1454 men and 0.066% (95%CI: 0.063-0.069) or one in 1523 for women. In the total and general population, the 10-yr age-conditional risk of HIV diagnosis showed that the highest risk of an HIV diagnosis is related to 30-yr -olds.

CONCLUSION

The estimated risks differed based on gender, age, and type of population. Paying close attention to these differences is critical for infection control planning and policies.

摘要

背景

鉴于传染病尤其是艾滋病毒的重要性,本研究旨在估计伊朗艾滋病毒诊断的终生风险和年龄条件风险。

方法

我们使用2011 - 2015年的生命统计数据、艾滋病毒监测数据和人口普查数据来计算特定年龄的艾滋病毒诊断率和非艾滋病毒死亡率。然后,考虑到竞争风险,将这些比率转换为艾滋病毒诊断的概率。最后,将这些概率应用于一个1000万活产的假设队列。通过Dev Can软件(版本6.7.4)计算伊朗总人口和一般人群中艾滋病毒诊断的终生风险和年龄条件风险。

结果

在总人口中,女性的终生风险为0.084%(95%置信区间:0.081 - 0.088),即1/1183;男性为0.21%(95%置信区间:0.201 - 0.211),即1/483。在一般人群中,男性的终生风险为0.069%(95%置信区间:0.066 - 0.072),即1/1454;女性为0.066%(95%置信区间:0.063 - 0.069),即1/1523。在总人口和一般人群中,10年年龄条件下的艾滋病毒诊断风险表明,艾滋病毒诊断的最高风险与30岁人群有关。

结论

估计的风险因性别、年龄和人群类型而异。密切关注这些差异对于感染控制规划和政策至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e4b/8223577/adde20573337/IJPH-50-1048-g001.jpg

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