Mohammed Mohammed Aliy, Abdurahman Fetulhak, Ayalew Yodit Abebe
School of Biomedical Engineering, Jimma Institute of Technology, Jimma University, Jimma, Ethiopia.
Faculty of Electrical and Computer Engineering, Jimma Institute of Technology, Jimma University, Jimma, Ethiopia.
BMC Biomed Eng. 2021 Jun 29;3(1):11. doi: 10.1186/s42490-021-00056-6.
Automating cytology-based cervical cancer screening could alleviate the shortage of skilled pathologists in developing countries. Up until now, computer vision experts have attempted numerous semi and fully automated approaches to address the need. Yet, these days, leveraging the astonishing accuracy and reproducibility of deep neural networks has become common among computer vision experts. In this regard, the purpose of this study is to classify single-cell Pap smear (cytology) images using pre-trained deep convolutional neural network (DCNN) image classifiers. We have fine-tuned the top ten pre-trained DCNN image classifiers and evaluated them using five class single-cell Pap smear images from SIPaKMeD dataset. The pre-trained DCNN image classifiers were selected from Keras Applications based on their top 1% accuracy.
Our experimental result demonstrated that from the selected top-ten pre-trained DCNN image classifiers DenseNet169 outperformed with an average accuracy, precision, recall, and F1-score of 0.990, 0.974, 0.974, and 0.974, respectively. Moreover, it dashed the benchmark accuracy proposed by the creators of the dataset with 3.70%.
Even though the size of DenseNet169 is small compared to the experimented pre-trained DCNN image classifiers, yet, it is not suitable for mobile or edge devices. Further experimentation with mobile or small-size DCNN image classifiers is required to extend the applicability of the models in real-world demands. In addition, since all experiments used the SIPaKMeD dataset, additional experiments will be needed using new datasets to enhance the generalizability of the models.
基于细胞学的宫颈癌筛查自动化可以缓解发展中国家熟练病理学家短缺的问题。到目前为止,计算机视觉专家已经尝试了许多半自动和全自动方法来满足这一需求。然而,如今,利用深度神经网络惊人的准确性和可重复性在计算机视觉专家中已变得很普遍。在这方面,本研究的目的是使用预训练的深度卷积神经网络(DCNN)图像分类器对单细胞巴氏涂片(细胞学)图像进行分类。我们对十个预训练的DCNN图像分类器进行了微调,并使用来自SIPaKMeD数据集的五类单细胞巴氏涂片图像对它们进行了评估。预训练的DCNN图像分类器是从Keras应用中根据其前1%的准确率挑选出来的。
我们的实验结果表明,从选定的十个预训练DCNN图像分类器中,DenseNet169表现最佳,其平均准确率、精确率、召回率和F1分数分别为0.990、0.974、0.974和0.974。此外,它比数据集创建者提出的基准准确率高出3.70%。
尽管与实验中的预训练DCNN图像分类器相比,DenseNet169的规模较小,但它仍不适合移动或边缘设备。需要对移动或小型DCNN图像分类器进行进一步实验,以扩展模型在实际需求中的适用性。此外,由于所有实验都使用了SIPaKMeD数据集,因此需要使用新数据集进行额外实验,以提高模型的通用性。