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Lemierre syndrome: the forgotten disease.勒米尔综合征:被遗忘的疾病。
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Jugular Vein Thrombosis and Anticoagulation Therapy in Lemierre's SyndromeA Post Hoc Observational and Population-Based Study of 82 Patients.勒米尔综合征中的颈静脉血栓形成与抗凝治疗:一项对82例患者的事后观察性和基于人群的研究
Open Forum Infect Dis. 2020 Nov 29;8(1):ofaa585. doi: 10.1093/ofid/ofaa585. eCollection 2021 Jan.
2
Lemierre syndrome: Current evidence and rationale of the Bacteria-Associated Thrombosis, Thrombophlebitis and LEmierre syndrome (BATTLE) registry.莱姆病相关性血栓形成、血栓性静脉炎和莱姆病(BATTLE)注册研究的现状:证据和原理。
Thromb Res. 2020 Dec;196:494-499. doi: 10.1016/j.thromres.2020.10.002. Epub 2020 Oct 8.
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Lemierre Syndrome: A Meta-analysis.勒米尔综合征:一项荟萃分析。
Int Arch Otorhinolaryngol. 2020 Jul;24(3):e379-e385. doi: 10.1055/s-0039-3402433. Epub 2020 Apr 24.
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Patients with Lemierre syndrome have a high risk of new thromboembolic complications, clinical sequelae and death: an analysis of 712 cases.莱姆病综合征患者存在发生新的血栓栓塞性并发症、临床后遗症和死亡的高风险:712 例病例分析。
J Intern Med. 2021 Mar;289(3):325-339. doi: 10.1111/joim.13114. Epub 2020 Jun 18.
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Lemierre syndrome - treat with antibiotics, anticoagulants or both?勒米尔综合征——用抗生素、抗凝剂治疗还是两者兼用?
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Lemierre's syndrome: A forgotten and re-emerging infection.勒米埃里氏综合征:一种被遗忘又重现的感染。
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The long shadow of lemierre's syndrome.莱姆病性关节炎的长期影响。
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Lemierre Syndrome: A Retrospective Study of the Role of Anticoagulation and Thrombosis Outcomes.勒米尔综合征:抗凝作用及血栓形成结局的回顾性研究
Acta Haematol. 2017;137(2):59-65. doi: 10.1159/000452855. Epub 2016 Dec 23.
9
Lemierre's syndrome: current perspectives on diagnosis and management.勒米尔综合征:诊断与管理的当前观点
Infect Drug Resist. 2016 Sep 14;9:221-227. doi: 10.2147/IDR.S95050. eCollection 2016.
10
A case of Lemierre's syndrome with septic shock and complicated parapneumonic effusions requiring intrapleural fibrinolysis.1例伴有感染性休克及需要胸腔内纤维蛋白溶解治疗的复杂性类肺炎性胸腔积液的勒米尔综合征。
Respir Med Case Rep. 2015 Aug 24;16:86-8. doi: 10.1016/j.rmcr.2015.08.007. eCollection 2015.

被遗忘的疾病:一例表现为软组织脓肿的莱米尔综合征非典型病例。

Forgotten disease: an atypical case of Lemierre syndrome presenting as a soft tissue abscess.

作者信息

Kumar Dilpat, Shamsi Wasif Elahi, Gomes Thales, Warsha Fnu

机构信息

Western Michigan University Homer Stryker MD School of Medicine, Kalamazoo, Michigan, USA

Internal Medicine, Western Michigan University School of Medicine, Kalamazoo, Michigan, USA.

出版信息

BMJ Case Rep. 2021 Jun 29;14(6):e242468. doi: 10.1136/bcr-2021-242468.

DOI:10.1136/bcr-2021-242468
PMID:34187798
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8245446/
Abstract

Lemierre syndrome (LS) is an acute oropharyngeal infection with secondary septic thrombophlebitis and distant septic embolisation. A 29-year-old woman with sore throat, dyspnoea and left shoulder pain, who was on levofloxacin for 3 days, presented with worsening symptoms. She was tachycardic, tachypneic and hypoxic on presentation. CT of neck and chest revealed multiple loculated abscesses on her left lower neck and shoulder, right peritonsillar abscess, thrombosis of the right external jugular vein and multiple bilateral septic emboli to the lungs. She was started on clindamycin and ampicillin sulbactam for LS. She developed septic shock and required intubation due to respiratory failure. Drainage of the left shoulder abscess grew After 2 weeks of a complicated intensive care unit stay, her haemodynamic status improved and she was transferred to the floor. LS has variable presentations, but regardless of the presentation, it is a potentially fatal disease-requiring prompt diagnosis and management.

摘要

勒米尔综合征(LS)是一种伴有继发性脓毒性血栓性静脉炎和远处脓毒性栓塞的急性口咽感染。一名29岁女性,咽痛、呼吸困难且左肩部疼痛,已服用左氧氟沙星3天,症状逐渐加重。就诊时她心动过速、呼吸急促且缺氧。颈部和胸部CT显示其左下颈部和肩部有多个分隔脓肿、右侧扁桃体周围脓肿、右颈外静脉血栓形成以及双肺多发双侧脓毒性栓子。她开始接受克林霉素和氨苄西林舒巴坦治疗LS。她出现了感染性休克,因呼吸衰竭需要插管。左肩部脓肿引流培养…… 在重症监护病房经历2周的复杂治疗后,她的血流动力学状态有所改善,被转至普通病房。LS有多种表现形式,但无论表现如何,它都是一种潜在的致命疾病,需要及时诊断和治疗。