Hasan Md Kamrul, Ara Iffat, Mondal Muhammad Shafiul Alam, Kabir Yearul
Department of Biochemistry and Molecular Biology, Tejgaon College, National University, Gazipur, 1704, Bangladesh.
Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka, 1000, Bangladesh.
Heliyon. 2021 Jun 7;7(6):e07240. doi: 10.1016/j.heliyon.2021.e07240. eCollection 2021 Jun.
Nature has always been an excellent source for many therapeutic compounds providing us with many medicinal plants and microorganisms producing beneficial chemicals. Therefore, the demand for medicinal plants, cosmetics, and health products is always on the rise. One such plant from the Leguminosae family is licorice and the scientific name is Linn. It is an herb-type plant with medicinal value. In the following article, we shall elaborately look at the plants' phytochemical constituents and the pharmacological impact of those substances. Several compounds such as glycyrrhizin, glycyrrhizinic acid, isoliquiritin, and glycyrrhizic acid have been found in this plant, which can provide pharmacological benefit to us with its anti-cancer, anti-atherogenic, anti-diabetic, anti-asthmatic, anti-inflammatory, anti-microbial, and antispasmodic activity. Alongside, these products have a different role in hepatoprotective, immunologic, memory-enhancing activity. They can stimulate hair growth, control obesity, and have anti-depressants, sedatives, and anticoagulant activity. This review examines recent studies on the phytochemical and pharmacological data and describes some side effects and toxicity of licorice and its bioactive components.
大自然一直是许多治疗性化合物的优质来源，为我们提供了许多能产生有益化学物质的药用植物和微生物。因此，对药用植物、化妆品和保健品的需求一直在增长。豆科植物中的一种这样的植物是甘草，其学名是甘草（Glycyrrhiza glabra Linn.）。它是一种具有药用价值的草本植物。在下面的文章中，我们将详细探讨该植物的植物化学成分以及这些物质的药理作用。在这种植物中发现了几种化合物，如甘草甜素、甘草次酸、异甘草素和甘草酸，它们具有抗癌、抗动脉粥样硬化、抗糖尿病、抗哮喘、抗炎、抗微生物和解痉活性，能为我们带来药理益处。此外，这些产物在保肝、免疫、增强记忆活性方面有不同作用。它们能刺激头发生长、控制肥胖，还具有抗抑郁、镇静和抗凝活性。本综述考察了关于植物化学成分和药理数据的近期研究，并描述了甘草及其生物活性成分的一些副作用和毒性。
