. Instituto de Medicina Integral Prof. Fernando Figueira - IMIP - Recife (PE) Brasil.
J Bras Pneumol. 2021 Jun 23;47(3):e20200473. doi: 10.36416/1806-3756/e20200473. eCollection 2021.
To measure peak inspiratory flow (PIF) and assess dynamic lung function in children and adolescents with asthma, as well as to determine the association of PIF with dynamic lung function and clinical variables.
This was a cross-sectional study of children and adolescents with asthma using dry powder inhalers (DPIs) regularly. The control group included sex-, age-, weight-, and height-matched individuals without lung disease. Socioeconomic and clinical variables were collected. PIF and dynamic lung function variables were obtained with a specific device. Between-group comparisons were made with the Student's t-test and ANOVA. Multiple linear regression analysis was performed, and Pearson's correlation coefficients were calculated to assess associations between PIF and the other variables.
A total of 88 individuals (44 asthma patients and 44 controls) participated in the study. PIF and respiratory muscle strength (S-index) values were lower in the asthma patients than in the controls. PIF correlated positively with age, weight, height, and S-index in the asthma group. After controlling for height, we found an increase of 0.05 units in PIF associated with an increase of 1 unit in the S-index in the asthma group.
PIF appears to be lower in children and adolescents with asthma than in those without asthma, correlating positively with age, height, weight, and respiratory muscle strength.
测量哮喘患儿和青少年的吸气峰流速（PIF）并评估其动态肺功能，并确定 PIF 与动态肺功能和临床变量的相关性。
这是一项使用干粉吸入器（DPIs）的哮喘患儿和青少年的横断面研究。对照组纳入性别、年龄、体重和身高匹配且无肺部疾病的个体。收集社会经济和临床变量。使用特定设备获取 PIF 和动态肺功能变量。采用学生 t 检验和方差分析进行组间比较。进行多元线性回归分析，并计算 Pearson 相关系数以评估 PIF 与其他变量之间的相关性。
共有 88 人（44 例哮喘患者和 44 例对照组）参与了研究。哮喘患者的 PIF 和呼吸肌力量（S 指数）值低于对照组。在哮喘组中，PIF 与年龄、体重、身高和 S 指数呈正相关。在校正身高后，我们发现哮喘组中 S 指数增加 1 个单位，PIF 增加 0.05 个单位。
哮喘患儿和青少年的 PIF 似乎低于无哮喘者，与年龄、身高、体重和呼吸肌力量呈正相关。
