城市封锁能否阻止 COVID-19 的传播?来自合成控制法的新证据。
Does city lockdown prevent the spread of COVID-19? New evidence from the synthetic control method.
机构信息
Harris School of Public Policy, University of Chicago, IL, 60637, Chicago, USA.
出版信息
Glob Health Res Policy. 2021 Jul 1;6(1):20. doi: 10.1186/s41256-021-00204-4.
BACKGROUND
At 10 a.m. on January 23, 2020 Wuhan, China imposed a 76-day travel lockdown on its 11 million residents in order to stop the spread of COVID-19. This lockdown represented the largest quarantine in the history of public health and provides us with an opportunity to critically examine the relationship between a city lockdown on human mobility and controlling the spread of a viral epidemic, in this case COVID-19. This study aims to assess the causal impact of the Wuhan lockdown on population movement and the increase of newly confirmed COVID-19 cases.
METHODS
Based on the daily panel data from 279 Chinese cities, our research is the first to apply the synthetic control approach to empirically analyze the causal relationship between the Wuhan lockdown of its population mobility and the progression of newly confirmed COVID-19 cases. By using a weighted average of available control cities to reproduce the counterfactual outcome trajectory that the treated city would have experienced in the absence of the lockdown, the synthetic control approach overcomes the sample selection bias and policy endogeneity problems that can arise from previous empirical methods in selecting control units.
RESULTS
In our example, the lockdown of Wuhan reduced mobility inflow by approximately 60 % and outflow by about 50 %. A significant reduction of new cases was observed within four days of the lockdown. The increase in new cases declined by around 50% during this period. However, the suppression effect became less discernible after this initial period of time. A 2.25-fold surge was found for the increase in new cases on the fifth day following the lockdown, after which it died down rapidly.
CONCLUSIONS
Our study provided urgently needed and reliable causal evidence that city lockdown can be an effective short-term tool in containing and delaying the spread of a viral epidemic. Further, the city lockdown strategy can buy time during which countries can mobilize an effective response in order to better prepare. Therefore, in spite of initial widespread skepticism, lockdowns are likely to be added to the response toolkit used for any future pandemic outbreak.
背景
2020 年 1 月 23 日上午 10 点,中国武汉对其 1100 万居民实施了为期 76 天的旅行封锁,以阻止 COVID-19 的传播。这次封锁代表了公共卫生史上最大规模的隔离,为我们提供了一个机会,可以批判性地审视城市封锁对人类流动性和控制病毒疫情传播之间的关系,在这种情况下是 COVID-19。本研究旨在评估武汉封锁对人口流动和新确诊 COVID-19 病例增加的因果影响。
方法
本研究基于 279 个中国城市的每日面板数据,首次应用综合控制方法对武汉封锁其人口流动与新确诊 COVID-19 病例进展之间的因果关系进行实证分析。通过使用可用控制城市的加权平均值来再现治疗城市在没有封锁情况下可能经历的反事实结果轨迹,综合控制方法克服了以往实证方法在选择控制单位时可能出现的样本选择偏差和政策内生性问题。
结果
在我们的例子中,武汉的封锁使流动人口流入量减少了约 60%,流出量减少了约 50%。封锁后四天内观察到新病例显著减少。在此期间,新病例的增加减少了约 50%。然而,在此初始时间段之后,抑制效果变得不那么明显。封锁后的第五天,新病例增加了 2.25 倍,之后迅速下降。
结论
本研究提供了急需的可靠因果证据,表明城市封锁可以成为控制和延迟病毒疫情传播的有效短期工具。此外,城市封锁策略可以争取时间,使各国能够动员有效的应对措施,以便更好地做好准备。因此,尽管最初普遍存在怀疑,但封锁可能会被添加到用于任何未来大流行爆发的应对工具包中。