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全球癌症死亡率上升而心血管疾病死亡率下降:未来影响

Cancer Mortality Rates Increasing vs Cardiovascular Disease Mortality Decreasing in the World: Future Implications.

作者信息

ReFaey Karim, Tripathi Shashwat, Grewal Sanjeet S, Bhargav Adip G, Quinones David J, Chaichana Kaisorn L, Antwi Samuel O, Cooper Leslie T, Meyer Fredric B, Dronca Roxana S, Diasio Robert B, Quinones-Hinojosa Alfredo

机构信息

Neurologic Surgery Department, Mayo Clinic, Jacksonville, FL.

National Center for Adaptive Neurotechnologies, Albany, NY.

出版信息

Mayo Clin Proc Innov Qual Outcomes. 2021 Jun 8;5(3):645-653. doi: 10.1016/j.mayocpiqo.2021.05.005. eCollection 2021 Jun.

Abstract

OBJECTIVE

To highlight the current global trends in mortality for cardiovascular disease and cancer.

METHODS

The World Health Organization and the World Bank DataBank databases were used to analyze mortality rates for cancer and cardiovascular disease by calculating age-standardized mortality rates (ASRs) from 2000 to 2015 for high-income, upper-middle-income, and lower-middle-income countries. Data for cancer mortality and population for 43 countries representing 5 of the 7 continents (except Australia and Antarctica) were analyzed.

RESULTS

From 2000 to 2015, there was an increase in the ASR for cancer for both men and women irrespective of a country's income status, representing an overall 7% increase in cancer ASR (Pearson , +0.99; <.00001). We report a higher ASR for cancer in high-income countries than in upper-middle-income and lower-middle-income countries specifically; high-income countries saw a 3% increase in cancer ASR vs +31% for upper-middle-income and +19% for lower-middle-income countries (<.01). There has been a decrease in the ASR for cardiovascular disease for the 15 years analyzed (<.00001). In addition, high-income countries had a higher ASR for cardiovascular disease than upper-middle-income countries during the 15-year period (<.05).

CONCLUSION

We suspect that because of early detection and targeted interventions, cardiovascular disease mortality rates have decreased during the past decade. On the basis of our results, cancer mortality rates continue to rise, with the projection of surpassing cardiovascular disease mortality rates in the near future.

摘要

目的

突出当前全球心血管疾病和癌症死亡率的趋势。

方法

利用世界卫生组织和世界银行数据库,通过计算2000年至2015年高收入、中高收入和中低收入国家的年龄标准化死亡率(ASR),分析癌症和心血管疾病的死亡率。分析了代表7个大洲中5个洲(不包括澳大利亚和南极洲)的43个国家的癌症死亡率和人口数据。

结果

2000年至2015年,无论国家收入状况如何,男性和女性的癌症ASR均有所上升,癌症ASR总体上升了7%(Pearson相关系数,r = +0.99;P <.00001)。我们报告称,高收入国家的癌症ASR高于中高收入和中低收入国家;高收入国家的癌症ASR上升了3%,而中高收入国家上升了31%,中低收入国家上升了19%(P <.01)。在所分析的15年中,心血管疾病的ASR有所下降(P <.00001)。此外,在这15年期间,高收入国家的心血管疾病ASR高于中高收入国家(P <.05)。

结论

我们怀疑,由于早期检测和针对性干预,过去十年中心血管疾病死亡率有所下降。根据我们的结果,癌症死亡率持续上升,预计在不久的将来将超过心血管疾病死亡率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b03/8240359/e77f710e58e8/gr1.jpg

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