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牙齿化学的新方法。牙釉质-牙本质交界处的定量分析。

Novel Approach to Tooth Chemistry. Quantification of the Dental-Enamel Junction.

机构信息

ComerLab Dorota Nowak, Radawiec Duży 196, 21-030 Motycz, Poland.

Department of Oral Medicine, Medical University of Lublin, 20-093 Lublin, Poland.

出版信息

Int J Mol Sci. 2021 Jun 2;22(11):6003. doi: 10.3390/ijms22116003.

DOI:10.3390/ijms22116003
PMID:34199407
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8199634/
Abstract

The dentin-enamel junction (DEJ) is known for its special role in teeth. Several techniques were applied for the investigation of the DEJ in human sound molar teeth. The electron (EPMA) and proton (PIXE) microprobes gave consistent indications about the variability of elemental concentrations on this boundary. The locally increased and oscillating concentrations of Mg and Na were observed in the junction, in the layer adhering to the enamel and covering roughly half of the DEJ width. The chemical results were compared with the optical profiles of the junction. Our chemical and optical results were next compared with the micromechanical results (hardness, elastic modulus, friction coefficient) available in the world literature. A strong correlation of both result sets was proven, which testifies to the self-affinity of the junction structures for different locations and even for different kinds of teeth and techniques applied for studies. Energetic changes in tooth strictly connected with crystallographic transformations were calculated, and the minimum energetic status was discovered for DEJ zone. Modeling of both walls of the DEJ from optical data was demonstrated. Comparing the DEJ in human teeth with the same structure found in dinosaur, shark, and alligator teeth evidences the universality of dentin enamel junction in animal world. The paper makes a contribution to better understanding the joining of the different hard tissues.

摘要

牙本质-釉质交界(DEJ)因其在牙齿中的特殊作用而闻名。已经应用了几种技术来研究人类健康磨牙的 DEJ。电子(EPMA)和质子(PIXE)微探针给出了关于此边界处元素浓度变化的一致指示。在交界处、附着在釉质上的层中观察到 Mg 和 Na 的局部浓度增加和波动,大约覆盖 DEJ 宽度的一半。化学结果与交界线的光学轮廓进行了比较。我们的化学和光学结果随后与世界文献中可用的微力学结果(硬度、弹性模量、摩擦系数)进行了比较。证明了这两个结果集之间存在很强的相关性,这证明了不同位置甚至不同类型的牙齿和用于研究的技术的交界结构的自相似性。与结晶转变严格相关的牙齿能量变化被计算出来,并且发现 DEJ 区域的最小能量状态。从光学数据对 DEJ 的两个壁进行建模。将人类牙齿中的 DEJ 与在恐龙、鲨鱼和鳄鱼牙齿中发现的相同结构进行比较,证明了牙本质釉质交界在动物界的普遍性。本文为更好地理解不同硬组织的连接做出了贡献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58a2/8199634/cdd820ae0370/ijms-22-06003-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58a2/8199634/40aa5b4df613/ijms-22-06003-g001a.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58a2/8199634/a49c1139d8a4/ijms-22-06003-g007a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58a2/8199634/6598718034e0/ijms-22-06003-g008a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58a2/8199634/cdd820ae0370/ijms-22-06003-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58a2/8199634/40aa5b4df613/ijms-22-06003-g001a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58a2/8199634/2818429d978c/ijms-22-06003-g002a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58a2/8199634/cff1b282cffb/ijms-22-06003-g003a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58a2/8199634/05b33cd51a78/ijms-22-06003-g004a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58a2/8199634/b69d0327af93/ijms-22-06003-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58a2/8199634/a409bc05d8cb/ijms-22-06003-g006a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58a2/8199634/a49c1139d8a4/ijms-22-06003-g007a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58a2/8199634/6598718034e0/ijms-22-06003-g008a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58a2/8199634/cdd820ae0370/ijms-22-06003-g009.jpg

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Int J Mol Sci. 2020 Dec 29;22(1):279. doi: 10.3390/ijms22010279.
2
Chemical gradients in human enamel crystallites.人类牙釉质晶体中的化学梯度。
Nature. 2020 Jul;583(7814):66-71. doi: 10.1038/s41586-020-2433-3. Epub 2020 Jul 1.
3
Tooth Enamel and its Dynamic Protein Matrix.牙釉质及其动态蛋白基质。
Molecules. 2022 Sep 9;27(18):5852. doi: 10.3390/molecules27185852.
4
Studies of Peculiar Mg-Containing and Oscillating Bioapatites in Sheep and Horse Teeth.绵羊和马牙齿中特殊含镁和振荡生物磷灰石的研究。
Biomolecules. 2021 Sep 30;11(10):1436. doi: 10.3390/biom11101436.
Int J Mol Sci. 2020 Jun 23;21(12):4458. doi: 10.3390/ijms21124458.
4
Novel Insights into Regulation of Human Teeth Biomineralization: Deciphering the Role of Post-Translational Modifications in a Tooth Protein Extract.新型人牙生物矿化调控机制研究:解析牙蛋白提取物中翻译后修饰的作用。
Int J Mol Sci. 2019 Aug 19;20(16):4035. doi: 10.3390/ijms20164035.
5
Type IV collagen is a novel DEJ biomarker that is reduced by radiotherapy.IV型胶原蛋白是一种新型的真皮表皮连接生物标志物,放疗会使其减少。
J Dent Res. 2014 Oct;93(10):1028-34. doi: 10.1177/0022034514548221. Epub 2014 Aug 21.
6
Type VII collagen is enriched in the enamel organic matrix associated with the dentin-enamel junction of mature human teeth.VII型胶原蛋白在与成熟人类牙齿牙本质-釉质交界处相关的釉质有机基质中含量丰富。
Bone. 2014 Jun;63:29-35. doi: 10.1016/j.bone.2014.02.012. Epub 2014 Mar 1.
7
Relationships between dentin and enamel mineral at the dentino-enamel boundary: electron tomography and high-resolution transmission electron microscopy study.牙本质-牙釉质界处牙本质与牙釉质矿物质之间的关系:电子断层扫描和高分辨率透射电子显微镜研究
Eur J Oral Sci. 2011 Dec;119 Suppl 1(Suppl 1):120-4. doi: 10.1111/j.1600-0722.2011.00876.x.
8
Coupled Nanomechanical and Raman Microspectroscopic Investigation of Human Third Molar DEJ.人第三磨牙牙本质-釉质界的纳米力学与拉曼显微光谱耦合研究
J Dent Biomech. 2010;2010. doi: 10.4061/2010/256903. Epub 2009 Aug 12.
9
Chemical/molecular structure of the dentin-enamel junction is dependent on the intratooth location.牙本质-釉质界的化学/分子结构取决于牙内位置。
Calcif Tissue Int. 2009 Mar;84(3):221-8. doi: 10.1007/s00223-008-9212-8. Epub 2009 Jan 18.
10
Physico-mechanical properties determination using microscale homotopic measurements: application to sound and caries-affected primary tooth dentin.使用微观同伦测量法测定物理机械性能:应用于健康及患龋乳恒牙本质
Acta Biomater. 2009 May;5(4):1338-48. doi: 10.1016/j.actbio.2008.10.023. Epub 2008 Nov 17.