吡咯里西啶生物碱：马达加斯加广受欢迎的饮料种子中的高毒性成分。
Pyrrolizidine-Derived Alkaloids: Highly Toxic Components in the Seeds of Used in Popular Beverages in Madagascar.
机构信息
Fundamental and Applied Biochemistry Department, Faculty of Sciences, University of Antananarivo, P.O. Box 906, Antananarivo 101, Madagascar.
Pharmacy Department, Faculty of Medicine, University of Antananarivo, P.O. Box 375, Antananarivo 101, Madagascar.
出版信息
Molecules. 2021 Jun 7;26(11):3464. doi: 10.3390/molecules26113464.
Seeds of (Fabaceae) are consumed in Madagascar in preparation of popular beverages. The investigation of extracts from the seeds of this species revealed the presence of high amounts of alkaloids from which two pyrrolizidine-derived alkaloids were isolated. One of them was fully characterized by spectroscopic and spectrometric methods, which was found to be usaramine. Owing to the high toxicity of these alkaloids, issuing a strong warning among populations consuming the seeds of must be considered.
马达加斯加人食用（豆科）的种子来制作流行的饮料。对该物种种子提取物的研究表明，其中含有大量生物碱，从中分离出两种吡咯里西啶衍生生物碱。其中一种通过光谱和光谱方法得到了充分的表征，被鉴定为乌沙胺。由于这些生物碱毒性很高，必须考虑向食用该种子的人群发出强烈警告。
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