抗色素天然化合物及其作用模式。
Anti-Pigmentary Natural Compounds and Their Mode of Action.
机构信息
College of Pharmacy, Ewha Womans University, Seodaemungu, Seoul 03760, Korea.
出版信息
Int J Mol Sci. 2021 Jun 8;22(12):6206. doi: 10.3390/ijms22126206.
Abstract
Hyper-activated melanocytes are the major cause of skin hyper-pigmentary disorders, such as freckles and melasma. Increasing efforts have been made to search for materials with depigmenting activity to develop functional cosmetics. As a result, numerous materials have been reported to have depigmenting activity but some of them are known to cause unwanted side effects. Consequently, anti-pigmentary natural compounds without concern of toxicity are in great demand. Virtually all sorts of natural sources have been investigated to find anti-pigmentary natural compounds. This review summarizes recently reported anti-pigmentary natural compounds and their mode of action from the ocean, plants, and bacteria.
摘要
高活性的黑色素细胞是导致皮肤色素沉着紊乱的主要原因，例如雀斑和黄褐斑。人们一直在努力寻找具有美白活性的物质，以开发功能性化妆品。因此，已经报道了许多具有美白活性的物质，但其中一些已知会引起不良反应。因此，人们非常需要没有毒性担忧的天然美白化合物。实际上，已经从海洋、植物和细菌等各种天然来源中寻找了天然美白化合物。本文综述了最近报道的海洋、植物和细菌来源的天然美白化合物及其作用机制。
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