Marques Adilson, Marconcin Priscila, Werneck André O, Ferrari Gerson, Gouveia Élvio R, Kliegel Matthias, Peralta Miguel, Ihle Andreas
CIPER, Faculty of Human Kinetics, University of Lisbon, 1499-002 Cruz Quebrada, Portugal.
ISAMB, University of Lisbon, 1649-004 Lisbon, Portugal.
Brain Sci. 2021 Jun 23;11(7):829. doi: 10.3390/brainsci11070829.
Physical activity (PA) may influence the secretion of neurotransmitters and thereby have positive consequences for an individual's vulnerability (i.e., reducing anxiety and depressive symptoms). This systematic review aims to analyse the potential bidirectional effects of exercise on dopamine from young adulthood to old age. The article search was conducted in PubMed, Scopus, and Web of Science in December 2020. The inclusion criteria were longitudinal and experimental study design; outcomes included dopamine and exercise; effect of exercise on dopamine and vice versa; adults; and articles published in English, Portuguese, or Spanish. Fifteen articles were included in the review. We observed robust findings concerning the potential effects of PA on dopamine, which notably seem to be observable across a wide range of participants characteristics (including age and sex), a variety of PA characteristics, and a broad set of methods to analyse dopamine. By contrast, regarding the potential effects of dopamine on PA, findings were mixed across studies. Thus, there are robust effects of physical exercise on dopamine. These findings further strengthen the idea that innovative approaches could include PA interventions for treating and preventing mental disorders. Therefore, it seems that PA is a potential alternative to deal with mental health issues.
身体活动（PA）可能会影响神经递质的分泌，从而对个体的易感性产生积极影响（即减轻焦虑和抑郁症状）。本系统综述旨在分析从青年到老年运动对多巴胺的潜在双向影响。2020年12月在PubMed、Scopus和科学网进行了文献检索。纳入标准为纵向和实验性研究设计；结果包括多巴胺和运动；运动对多巴胺的影响及反之亦然；成年人；以及以英文、葡萄牙文或西班牙文发表的文章。该综述纳入了15篇文章。我们观察到了关于PA对多巴胺潜在影响的有力发现，这些影响在广泛的参与者特征（包括年龄和性别）、各种PA特征以及分析多巴胺的一系列广泛方法中似乎都很明显。相比之下，关于多巴胺对PA的潜在影响，各研究结果不一。因此，体育锻炼对多巴胺有显著影响。这些发现进一步强化了这样一种观点，即创新方法可以包括采用PA干预措施来治疗和预防精神障碍。因此，PA似乎是应对心理健康问题的一种潜在替代方法。
