Baumann Carmen, Almarzooqi Ahmed, Blobner Katharina, Zapp Daniel, Kirchmair Katharina, Schwer Lydia S, Lohmann Chris P, Kaye Stephen B
Ophthalmology Department, Technical University of Munich (TUM), 81675 Munich, Germany.
Department of Eye and Vision Science, University of Liverpool, William Henry Duncan Building, 6 West Derby Street, Liverpool L7 8TX, UK.
J Clin Med. 2021 Jun 29;10(13):2899. doi: 10.3390/jcm10132899.
The purpose of this study was to assess the repeatability and reproducibility of measuring the minimum linear diameter (MLD) of macular holes (MHs) using horizontal linear and radial scan modes in optical coherence tomography (OCT). Patients with concurrent sets of radial and horizontal linear OCT volume scans were included. The MLD was measured twice in both scan modes by six raters of three different experience levels (groups). Outcome measures were the reliability and repeatability of MLD measurements. Fifty patients were included. Mean MLD was 317.21(±170.63) µm in horizontal linear and 364.52 (±161.71) µm in radial mode, a difference of 47.31 (±26.48) µm ( < 0.001). In the radial scan mode, MLD was identified within 15° of the horizontal meridian in 27% and within 15° of the vertical meridian in 26.7%, with the remainder (46.3%) in oblique meridians. The intra-group coefficients of repeatability (CR) for horizontal linear mode were 23 µm, 33 µm and 45 µm, and for radial mode 25 µm, 44 µm and 57 µm for groups 1, 2 and 3, respectively. The inter-group CR, taking group 1 as reference standard for groups 2 and 3, were 74 µm and 71 µm for the linear mode, and 62 µm and 78 µm for radial mode. The radial mode provides good repeatability and reliability for measurement of MLD. In a majority of cases the MLD does not lie in the horizontal meridian and would be underestimated using a horizontal OCT mode.
本研究的目的是评估在光学相干断层扫描（OCT）中使用水平线性扫描和径向扫描模式测量黄斑裂孔（MH）最小线性直径（MLD）的可重复性和再现性。纳入同时进行了径向和水平线性OCT容积扫描的患者。由三名不同经验水平（组）的六名评估者在两种扫描模式下对MLD进行两次测量。结果指标为MLD测量的可靠性和可重复性。共纳入50例患者。水平线性模式下的平均MLD为317.21（±170.63）µm，径向模式下为364.52（±161.71）µm，差值为47.31（±26.48）µm（<0.001）。在径向扫描模式下，27%的MLD在水平子午线15°范围内确定，26.7%在垂直子午线15°范围内确定，其余（46.3%）在斜子午线上。第1组、第2组和第3组水平线性模式的组内重复性系数（CR）分别为23 µm、33 µm和45 µm，径向模式分别为25 µm、44 µm和57 µm。以第1组为第2组和第3组的参考标准，线性模式的组间CR分别为74 µm和71 µm，径向模式为62 µm和78 µm。径向模式为MLD测量提供了良好的可重复性和可靠性。在大多数情况下，MLD不在水平子午线上，使用水平OCT模式会低估MLD。
