Marinescu Elena-Alexandra, Nica Oliviu, Ilinoiu Enio, Cojocaru Anca, Negrilă Alina Alexandra, Ciurea Marius Eugen
Department of Plastic Surgery, University of Medicine and Pharmacy of Craiova.
Plastic surgery Clinic, Emergency County Hospital of Craiova.
Curr Health Sci J. 2021 Jan-Mar;47(1):42-48. doi: 10.12865/CHSJ.47.01.07. Epub 2021 Mar 31.
Observing the positive effects of PRP (platelet-rich plasma) used in various pathologies, both in traumatology, orthopedics, sports medicine, and in plastic and reconstructive surgery, we decided to develop an improved product, using granular hyaluronic acid. The paper aims at establishing a protocol for obtaining PRP enriched with hyaluronic acid, which can be used in the current practice of treatment of skin defects, safely, with minimal side effects and limited possible, but to provide a shorter healing period as compared to native, "free" healing. The experiment aims to find an effective and rapid method of healing wounds with skin defects, by using a local adjuvant (PRP enriched with hyaluronic acid), which is available to any plastic surgeon. Following the combination of PRP with granular hyaluronic acid, we obtained a product that macroscopically has a gelatinous, viscous consistency, with a good adhesion to the tissues. The potential benefits of this experiment could be the basis for the development of treatment protocols for various pathologies, which result in wounds with skin defects, the most important aspect being the shortening of the classic healing period.
观察到富血小板血浆（PRP）在创伤学、骨科、运动医学以及整形和重建外科等各种病症中所产生的积极效果后，我们决定研发一种使用颗粒状透明质酸的改良产品。本文旨在建立一种获取富含透明质酸的PRP的方案，该方案可安全地用于当前皮肤缺损治疗实践中，副作用最小且可能性有限，但与自然的“无辅助”愈合相比，能提供更短的愈合期。该实验旨在通过使用一种任何整形外科医生都可获取的局部佐剂（富含透明质酸的PRP），找到一种有效且快速治愈皮肤缺损伤口的方法。将PRP与颗粒状透明质酸结合后，我们得到了一种在宏观上具有凝胶状、粘稠质地且对组织有良好粘附性的产品。该实验的潜在益处可能成为各种导致皮肤缺损伤口的病症治疗方案开发的基础，其中最重要的方面是缩短传统愈合期。
