• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

[磨牙症性切牙矿化不全（MIH）——关于患病率和病因的讨论，特别参考慕尼黑出生队列GINIplus和LISA的研究结果]

[Molar incisor hypomineralisation (MIH)-discussion of prevalence and etiology with special reference to the results from the Munich birth cohorts GINIplus and LISA].

作者信息

Kühnisch Jan, Standl Marie, Hickel Reinhard, Heinrich Joachim

机构信息

Poliklinik für Zahnerhaltung und Parodontologie, Klinikum der Universität München, Ludwig-Maximilians-Universität München, München, Deutschland.

Institut für Epidemiologie, Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt, Neuherberg, Deutschland.

出版信息

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2021 Aug;64(8):924-930. doi: 10.1007/s00103-021-03366-1. Epub 2021 Jul 2.

DOI:10.1007/s00103-021-03366-1
PMID:34213569
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8316183/
Abstract

After caries, molar incisor hypomineralisation (MIH)-also known as chalky teeth-is one the most common dental diseases in children and adolescents. In addition to aesthetic limitations, especially on the anterior teeth, hypersensitivities and enamel breakdowns on permanent molars are of functional importance. While the MIH prevalence rates range from ~ 10% to ~ 30% and is well described, the situation regarding aetiology is unsatisfactory. Although efforts have been made in the past to clarify the aetiology, no plausible reason is available so far. Aetiology research has to be judged as methodologically challenging, since it should ideally be embedded in prospectively planned birth cohort studies. The aim of this article is to summarize typical clinical characteristics of MIH, epidemiological findings and potential causes with special reference to the earlier published results from the two Munich birth cohort studies GINIplus and LISA.

摘要

继龋齿之后，磨牙切牙矿化不全（MIH）——也被称为白垩牙——是儿童和青少年中最常见的牙科疾病之一。除了美观受限，尤其是在前牙上，恒牙磨牙的过敏和牙釉质破损具有功能上的重要性。虽然MIH的患病率在10%至30%之间且已有充分描述，但病因情况仍不尽人意。尽管过去已努力阐明病因，但目前尚无合理的原因。病因学研究在方法上具有挑战性，因为理想情况下它应纳入前瞻性规划的出生队列研究中。本文旨在总结MIH的典型临床特征、流行病学研究结果及潜在病因，并特别参考慕尼黑两项出生队列研究GINIplus和LISA早期发表的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9aec/8316183/50eef4ea0834/103_2021_3366_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9aec/8316183/1c8bdc441b98/103_2021_3366_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9aec/8316183/026e28f7eb07/103_2021_3366_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9aec/8316183/50eef4ea0834/103_2021_3366_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9aec/8316183/1c8bdc441b98/103_2021_3366_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9aec/8316183/026e28f7eb07/103_2021_3366_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9aec/8316183/50eef4ea0834/103_2021_3366_Fig3_HTML.jpg

相似文献

1
[Molar incisor hypomineralisation (MIH)-discussion of prevalence and etiology with special reference to the results from the Munich birth cohorts GINIplus and LISA].[磨牙症性切牙矿化不全（MIH）——关于患病率和病因的讨论，特别参考慕尼黑出生队列GINIplus和LISA的研究结果]
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2021 Aug;64(8):924-930. doi: 10.1007/s00103-021-03366-1. Epub 2021 Jul 2.
2
Molar incisor hypomineralisation and dental caries among children in Slovenia.斯洛文尼亚儿童的磨牙和切牙釉质发育不全与龋齿。
Eur J Paediatr Dent. 2013 Sep;14(3):241-5.
3
Molar Incisor Hypomineralisation: Current Knowledge and Practice.恒磨牙牙釉质发育不全：当前知识与实践
Int Dent J. 2021 Aug;71(4):285-291. doi: 10.1111/idj.12624. Epub 2021 Jan 27.
4
Is There an Association between Asthma and Dental Caries and Molar Incisor Hypomineralisation?哮喘与龋齿和磨牙切牙矿化不全之间是否存在关联？
Caries Res. 2020;54(1):87-95. doi: 10.1159/000504382. Epub 2019 Nov 29.
5
Molar incisor hypomineralisation (MIH).磨牙切牙矿化不全（MIH）。
Eur J Paediatr Dent. 2003 Sep;4(3):114-20.
6
Prevalence of molar-incisor-hypomineralisation among children participating in the Dutch National Epidemiological Survey (2003).参与荷兰全国流行病学调查（2003年）的儿童中磨牙-切牙矿化不全的患病率。
Eur Arch Paediatr Dent. 2008 Dec;9(4):218-23. doi: 10.1007/BF03262638.
7
Was molar incisor hypomineralisation (MIH) present in archaeological case series?考古病例系列中是否存在磨牙切牙矿化不全（MIH）？
Clin Oral Investig. 2016 Dec;20(9):2387-2393. doi: 10.1007/s00784-016-1717-3. Epub 2016 Jan 18.
8
Relationship between caries experience and demarcated hypomineralised lesions (including MIH) in the permanent dentition of 15-year-olds.15 岁恒牙的龋病经历与界限明确的低矿化病变（包括 MIH）之间的关系。
Clin Oral Investig. 2018 Jun;22(5):2013-2019. doi: 10.1007/s00784-017-2299-4. Epub 2017 Dec 9.
9
Molar incisor hypomineralisation in a group of children and adolescents living in Dresden (Germany).居住在德国德累斯顿的一组儿童和青少年中的磨牙和切牙矿化不全情况。
Eur J Paediatr Dent. 2003 Sep;4(3):133-7.
10
Best clinical practice guidance for clinicians dealing with children presenting with molar-incisor-hypomineralisation (MIH): an updated European Academy of Paediatric Dentistry policy document.临床医生处理低龄儿童前磨牙-切牙釉质发育不全（MIH）临床实践指南：欧洲儿童牙科学会更新的政策文件。
Eur Arch Paediatr Dent. 2022 Feb;23(1):3-21. doi: 10.1007/s40368-021-00668-5. Epub 2021 Oct 20.

引用本文的文献

1
Current Knowledge of the Etiology and Management of Molar Incisor Hypomineralization in Children: A Narrative Review.儿童磨牙切牙矿化不全的病因及管理现状：一项叙述性综述
Cureus. 2024 Nov 29;16(11):e74770. doi: 10.7759/cureus.74770. eCollection 2024 Nov.
2
Is there a rise of prevalence for Molar Incisor Hypomineralization? A meta-analysis of published data.磨牙切牙矿化不全的患病率是否上升？已发表数据的荟萃分析。
BMC Oral Health. 2024 Jan 25;24(1):127. doi: 10.1186/s12903-023-03637-0.

本文引用的文献

1
Gene-environment interaction in molar-incisor hypomineralization.基因-环境在磨牙-切牙釉质发育不全中的相互作用。
PLoS One. 2021 Jan 6;16(1):e0241898. doi: 10.1371/journal.pone.0241898. eCollection 2021.
2
Comparison of four different treatment strategies in teeth with molar-incisor hypomineralization-related enamel breakdown-A retrospective cohort study.四种不同治疗策略在磨牙-切牙釉质发育不全相关釉质破坏患牙中的比较：一项回顾性队列研究。
Int J Paediatr Dent. 2020 Sep;30(5):597-606. doi: 10.1111/ipd.12636. Epub 2020 Mar 20.
3
Is There an Association between Asthma and Dental Caries and Molar Incisor Hypomineralisation?
哮喘与龋齿和磨牙切牙矿化不全之间是否存在关联？
Caries Res. 2020;54(1):87-95. doi: 10.1159/000504382. Epub 2019 Nov 29.
4
Association of High-Dose Vitamin D Supplementation During Pregnancy With the Risk of Enamel Defects in Offspring: A 6-Year Follow-up of a Randomized Clinical Trial.孕期补充高剂量维生素D与后代牙釉质缺陷风险的关联：一项随机临床试验的6年随访
JAMA Pediatr. 2019 Oct 1;173(10):924-930. doi: 10.1001/jamapediatrics.2019.2545.
5
A systematic review and meta-analysis of systemic exposure associated with molar incisor hypomineralization.系统评价和荟萃分析与恒切牙釉质发育不全相关的全身暴露情况。
Community Dent Oral Epidemiol. 2019 Oct;47(5):407-415. doi: 10.1111/cdoe.12467. Epub 2019 May 20.
6
On the Variable Clinical Presentation of Molar-Incisor Hypomineralization.关于磨牙-切牙牙釉质发育不全的多变临床表现。
Caries Res. 2019;53(4):482-488. doi: 10.1159/000496542. Epub 2019 Apr 3.
7
Foetal, neonatal and child vitamin D status and enamel hypomineralization.胎儿、新生儿及儿童的维生素D状况与釉质矿化不全
Community Dent Oral Epidemiol. 2018 Aug;46(4):343-351. doi: 10.1111/cdoe.12372. Epub 2018 Mar 1.
8
Relationship between caries experience and demarcated hypomineralised lesions (including MIH) in the permanent dentition of 15-year-olds.15 岁恒牙的龋病经历与界限明确的低矿化病变（包括 MIH）之间的关系。
Clin Oral Investig. 2018 Jun;22(5):2013-2019. doi: 10.1007/s00784-017-2299-4. Epub 2017 Dec 9.
9
Global burden of molar incisor hypomineralization.恒牙切牙釉质发育不全的全球负担。
J Dent. 2018 Jan;68:10-18. doi: 10.1016/j.jdent.2017.12.002. Epub 2017 Dec 6.
10
The Würzburg MIH concept: the MIH treatment need index (MIH TNI) : A new index to assess and plan treatment in patients with molar incisior hypomineralisation (MIH).维尔茨堡磨牙切牙低矿化（MIH）概念：MIH治疗需求指数（MIH TNI）：一种评估和规划磨牙切牙低矿化（MIH）患者治疗的新指数。
Eur Arch Paediatr Dent. 2017 Oct;18(5):355-361. doi: 10.1007/s40368-017-0301-0. Epub 2017 Sep 14.