Laboratory Herbal of Materia Medica Batu, Public Health Office of East Java Province, Batu, Indonesia.
J Basic Clin Physiol Pharmacol. 2021 Jun 25;32(4):755-759. doi: 10.1515/jbcpp-2020-0396.
Antibiotic treatments can create multi-drug resistance among several pathogens. There is a need for an antibiotic alternative to overcome this problem. In Indonesia, (Asiatic pennywort) and (string bamboo) are two common medicinal plants used to treat tuberculosis, diarrhea, and other symptoms. This study was done to compare the antimicrobial activity of and against five pathogenic bacteria, i.e., H37Rv strain, , , , and .
The ethanol extracts of , and shoot were obtained by using speed extractor, pressure, and temperature extraction. The phytochemical contents of each extract were screened. The ethanol extract's antimycobacterial activity was determined using Lowenstein Jensen (LJ) medium and antibacterial activity was determined using Kirby-Bauer methods on Mueller Hinton agar (MHA).
The phytochemical analysis showed that extract contains alkaloids and tannins, whereas extract contains flavonoids, alkaloids, saponins, and tannins. This study showed that inhibited the growth of H37Rv strain and . showed antimicrobial activity against all pathogenic bacteria tested, except .
Both medicinal plants extract can inhibit the growth of five pathogenic bacteria tested, thus, have the potential as an alternative treatment, or complementary, to treat the pathogenic bacterial infection.
抗生素治疗会导致多种病原体产生耐药性。因此，需要一种抗生素替代品来解决这个问题。在印度尼西亚，（积雪草）和（吊竹梅）是两种常用的药用植物，用于治疗肺结核、腹泻和其他症状。本研究旨在比较 和 对五种病原菌（H37Rv 株、 、 、 和 ）的抗菌活性。
采用快速提取器、加压和温度提取法提取 和 茎的乙醇提取物。对每种提取物的植物化学成分进行筛选。使用 Lowenstein Jensen（LJ）培养基测定乙醇提取物的抗分枝杆菌活性，采用 Kirby-Bauer 方法在 Mueller Hinton 琼脂（MHA）上测定抗菌活性。
植物化学分析表明， 提取物含有生物碱和单宁，而 提取物含有类黄酮、生物碱、皂苷和单宁。本研究表明， 抑制 H37Rv 株和 的生长。 对所有测试的病原菌均显示出抗菌活性，除 外。
两种药用植物提取物都能抑制五种测试病原菌的生长，因此具有作为替代治疗或补充治疗治疗病原菌感染的潜力。
