Vita-Salute San Raffaele University, Milan, Italy.
University of Minnesota, Minneapolis, MN, USA.
J Psychiatr Res. 2021 Sep;141:146-151. doi: 10.1016/j.jpsychires.2021.06.024. Epub 2021 Jun 15.
The present study aimed to evaluate base rate estimates, course of, and psychopathology and personality risk factors for COVID-19-related post-traumatic stress disorder (PTSD) in community-dwelling adults during the pandemic. 203 participants from a sample of 811 Italian community-dwelling adults agreed to participate in a nine-month, three-wave (Wave 1: March 2020; Wave 2: June 2020; Wave 3: December 2020) longitudinal study. Participants in the longitudinal study did not differ from the cross-sectional original sample on age, gender, civil status, educational level, occupation, and Italian area of residence. At each wave, participants were administered the PTSD scale of the International Trauma Questionnaire (ITQ), DSM-5 measures of acute stress, dissociation, depression and anxiety, as well as a maladaptive personality domain measure at Wave 1. Participants were instructed to answer to the ITQ items based only on COVID-19 pandemic and related containment measures. The point prevalence estimates of COVID-19 related PTSD at each wave ranged from 11% to 13%; however, up to roughly 23% of our participants experienced clinically relevant PTSD features during nine months of the COVID-19 pandemic in Italy. Multiple logistic regression results showed that experiencing internalizing symptoms (i.e., mostly acute stress) and selected personality features (i.e., Negative Affectivity and Psychoticism) at Wave 1 represent risk factors for PTSD symptoms at later waves. These findings extend previous knowledge on COVID-19 related PTSD and support the need for preventive and treatment interventions for PTSD during the COVID-19 pandemic.
本研究旨在评估大流行期间社区居住成年人的 COVID-19 相关创伤后应激障碍(PTSD)的基础比率估计、病程以及精神病理学和人格风险因素。从意大利社区居住的 811 名成年人样本中,203 名参与者同意参加一项为期九个月、三个波次(波 1:2020 年 3 月;波 2:2020 年 6 月;波 3:2020 年 12 月)的纵向研究。参与纵向研究的参与者在年龄、性别、婚姻状况、教育水平、职业和意大利居住地区方面与横断面原始样本无差异。在每一波中,参与者都接受了国际创伤问卷(ITQ)的 PTSD 量表、DSM-5 急性应激、分离、抑郁和焦虑的测量,以及波 1 的适应不良人格领域的测量。参与者被指示仅根据 COVID-19 大流行和相关遏制措施回答 ITQ 项目。每一波 COVID-19 相关 PTSD 的点患病率估计值在 11%至 13%之间;然而,在意大利 COVID-19 大流行的九个月中,约有 23%的参与者经历了临床相关的 PTSD 特征。多元逻辑回归结果表明,在第 1 波时经历内在症状(即主要是急性应激)和特定的人格特征(即负性情感和精神病性)是后期 PTSD 症状的风险因素。这些发现扩展了 COVID-19 相关 PTSD 的先前知识,并支持在 COVID-19 大流行期间对 PTSD 进行预防和治疗干预的必要性。