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一项对200例患者的回顾性研究:采用中线皮质骨轨迹螺钉固定的微创脊柱手术治疗腰椎退行性疾病

Minimally Invasive Spine Surgery With Midline Cortical Bone Trajectory Screw Fixation for Lumbar Degenerative Disease in a Retrospective Study of 200 Patients.

作者信息

Noh Sung Hyun, Zhang Ho Yeol

机构信息

Department of Neurosurgery, National Health Insurance Service Ilsan Hospital, Goyang, Korea.

Department of Neurosurgery, Yonsei University College of Medicine, Seoul, Korea.

出版信息

Neurospine. 2021 Jun;18(2):355-362. doi: 10.14245/ns.2142016.008. Epub 2021 Jun 30.

Abstract

OBJECTIVE

Midline lumbar interbody fusion is performed for treatment of various lumbar degenerative diseases, with good clinical outcomes and few complications. However, there are no large-scale or long-term studies regarding midline lumbar interbody fusion. Therefore, the purpose of this study was to evaluate the clinical results of midline lumbar interbody fusion and to compare the results according to surgical level.

METHODS

Between January 2013 and December 2015, 200 patients with lumbar degenerative disease undergoing midline lumbar interbody fusion surgery were enrolled. The mean patient age was 69.9 ± 15.8 years (range, 40-85 years). The patients were divided into groups according to surgical level: (1) level 1 operation (136 patients), (2) level 2 operation (43 patients), (3) level 3 operation (12 patients), and (4) level 4 or higher (9 patients). Clinical outcomes, fusion rates, and complications were compared among the 4 groups.

RESULTS

All clinical outcomes significantly improved after surgery (measured at 3 years postoperatively) in all groups. Mean fusion rate was 90.5% ± 5.21%. Fusion rate was highest in group I (95.8%) and lowest in group IV (85.2%). There were complications in 17 cases (8.5%). Adjacent segment disease occurred in 16 cases, 5 of which required surgery. Group 1 had 1 case, and group 4 had 4 cases. Screw loosening occurred in 1 case in group 4. There were no cases of infection or mechanical complications.

CONCLUSION

This large, single-institution, retrospective study demonstrates favorable clinical outcomes after midline lumbar interbody fusion for lumbar degenerative disease regardless of surgical level.

摘要

目的

腰椎后路椎间融合术用于治疗各种腰椎退行性疾病,临床疗效良好且并发症较少。然而,目前尚无关于腰椎后路椎间融合术的大规模或长期研究。因此,本研究的目的是评估腰椎后路椎间融合术的临床效果,并根据手术节段比较结果。

方法

2013年1月至2015年12月,纳入200例行腰椎后路椎间融合术的腰椎退行性疾病患者。患者平均年龄为69.9±15.8岁(范围40 - 85岁)。根据手术节段将患者分为四组:(1)1级手术(136例),(2)2级手术(43例),(3)3级手术(12例),(4)4级及以上手术(9例)。比较四组患者的临床疗效、融合率及并发症情况。

结果

所有组术后(术后3年测量)所有临床疗效均显著改善。平均融合率为90.5%±5.21%。融合率在第I组最高(95.8%),在第IV组最低(85.2%)。有17例(8.5%)出现并发症。发生相邻节段疾病16例,其中5例需要手术治疗。第1组1例,第4组4例。第4组有1例发生螺钉松动。无感染或机械并发症病例。

结论

这项大型的单机构回顾性研究表明,无论手术节段如何,腰椎后路椎间融合术治疗腰椎退行性疾病均具有良好的临床效果。

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