Swain Jason E
CCRM IVF Network, Lone Tree, Colorado.
F S Rep. 2020 Nov 11;2(1):133-135. doi: 10.1016/j.xfre.2020.10.010. eCollection 2021 Mar.
How embryos are cultured, in groups or individually, can influence their development and have other unforeseen impacts on subsequent assisted reproductive technologies. Although a group culture of embryos improves the blastocyst formation rates, this can create conditions wherein separate blastocysts may fuse. This fusion of 2 blastocysts can create unique logistic issues for embryo biopsy and genetic analysis. New culture approaches have emerged to facilitate individual embryo culture without losing the benefit of the group culture approach. Unique culture dishes and adjustments of laboratory culture/embryo handling protocols offer possible solutions to minimize or avoid blastocyst fusion.
胚胎是成组培养还是单独培养，会影响其发育，并对后续辅助生殖技术产生其他不可预见的影响。虽然胚胎的成组培养提高了囊胚形成率，但这可能会创造出分离的囊胚可能融合的条件。两个囊胚的这种融合会给胚胎活检和基因分析带来独特的后勤问题。新的培养方法已经出现，以促进单个胚胎培养，同时又不失去成组培养方法的益处。独特的培养皿以及实验室培养/胚胎处理方案的调整提供了可能的解决方案，以尽量减少或避免囊胚融合。
