营养不良与酒精性肝炎
Malnutrition and Alcohol-Associated Hepatitis.
机构信息
Division of Gastroenterology, Hepatology and Nutrition, University of Louisville School of Medicine, 505 South Hancock Street, Louisville, KY 40202, USA; UofL Alcohol Research Center, University of Louisville, Louisville, KY, USA; Department of Medicine, University of Louisville, Louisville, KY, USA; Hepatobiology and Toxicology Center, University of Louisville, Louisville, KY, USA; Robely Rex Veterans Affairs Medical Center, Louisville, KY 40207, USA.
Division of Gastroenterology, Hepatology and Nutrition, University of Louisville School of Medicine, 505 South Hancock Street, Louisville, KY 40202, USA.
出版信息
Clin Liver Dis. 2021 Aug;25(3):557-570. doi: 10.1016/j.cld.2021.03.002. Epub 2021 May 26.
Malnutrition is common in alcohol-associated hepatitis (AH); almost all patients with severe AH have some component of malnutrition. The classic phenotype of malnutrition in AH is sarcopenia, but this has become more difficult to discern clinically as patients have become more obese. Patients with AH are often drinking 10 to 15 standard drinks per day. This substantial alcohol consumption becomes a major source of calories, but these are considered "empty" calories that contain little nutritional value. Malnutrition is associated with liver complications, such as hepatic encephalopathy, and worse liver outcomes. Nutrition support can improve nutrition status and reduce complications.
营养不良在酒精性肝炎（AH）中很常见；几乎所有重症 AH 患者都存在一定程度的营养不良。AH 中营养不良的典型表型是肌肉减少症，但随着患者肥胖程度的增加，临床上更难识别这种情况。AH 患者通常每天饮酒 10 至 15 标准份。这种大量饮酒成为热量的主要来源，但这些被认为是“空”卡路里，几乎没有营养价值。营养不良与肝并发症有关，如肝性脑病和更差的肝脏结局。营养支持可以改善营养状况并减少并发症。
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