Division of Neonatology
Department of Economics, Rider University and National Bureau of Economic Research, Lawrenceville, New Jersey.
Pediatrics. 2021 Aug;148(2). doi: 10.1542/peds.2020-021287. Epub 2021 Jul 9.
To estimate associations between gestational age (GA) and teacher-reported academic outcomes at age 9 years among children born at term (37-41 weeks).
A secondary data analysis of 1405 children participating in a national US birth cohort study was conducted. At age 9 years, students were evaluated by their teachers in the areas of mathematics, science and social studies, and language and literacy. Unadjusted and adjusted logistic regression models of associations between GA and teacher-reported academic outcomes were estimated and neonatal morbidities were explored as potential pathways.
A continuous measure of GA in weeks was significantly associated with above-average rankings in all areas. The associations were similar across outcomes (eg, mathematics [odds ratio (OR): 1.13; confidence interval (CI): 1.02-1.25], science and social studies [OR: 1.13; CI: 1.01-1.26], and language and literacy [OR: 1.16; CI: 1.05-1.28]) in a model that adjusted for child sex, maternal characteristics, and obstetric risk factors and delivery complications. Other specifications indicate a positive association between late term (41 weeks) and mathematics and a negative association between early term (37-38 weeks) and language and literacy, compared with term (39-40). The associations did not appear to operate through neonatal morbidity.
The findings highlight the importance of GA, even at term. Whereas current guidelines suggest waiting until at least 39 weeks to deliver when possible, our findings add to a small group of studies suggesting that GA through 41 weeks is associated with improvements in some educational outcomes.
评估足月(37-41 周)出生的儿童在 9 岁时的胎龄(GA)与教师报告的学业成绩之间的关联。
对参加美国国家出生队列研究的 1405 名儿童进行了二次数据分析。在 9 岁时,学生的数学、科学和社会研究、语言和读写能力等领域由他们的老师进行评估。采用未调整和调整后的逻辑回归模型,估计 GA 与教师报告的学业成绩之间的关联,并探讨新生儿发病率作为潜在途径。
以周为单位的连续 GA 测量值与所有领域的平均以上排名显著相关。在调整了儿童性别、产妇特征以及产科风险因素和分娩并发症的模型中,结果在不同结局中相似(例如,数学[比值比(OR):1.13;置信区间(CI):1.02-1.25]、科学和社会研究[OR:1.13;CI:1.01-1.26]以及语言和读写能力[OR:1.16;CI:1.05-1.28])。其他规格表明,与足月(39-40 周)相比,晚期(41 周)与数学呈正相关,而早期(37-38 周)与语言和读写能力呈负相关。这些关联似乎并非通过新生儿发病率起作用。
这些发现强调了 GA 的重要性,即使是在足月的情况下。虽然目前的指南建议在可能的情况下至少等到 39 周后再分娩,但我们的研究结果增加了一小部分研究的结果,表明在 41 周内的 GA 与一些教育成果的提高有关。