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J Orthop Surg Res. 2021 Jan 14;16(1):59. doi: 10.1186/s13018-021-02210-1.
2
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Anthocyanins in Brassicaceae: composition, stability, bioavailability, and potential health benefits.芸薹属植物中的花色苷:组成、稳定性、生物利用度和潜在健康益处。
Crit Rev Food Sci Nutr. 2022;62(8):2205-2220. doi: 10.1080/10408398.2020.1852170. Epub 2020 Dec 1.
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天然和合成蓝色染料对人体健康的影响:当前知识与治疗前景综述

The Effects of Natural and Synthetic Blue Dyes on Human Health: A Review of Current Knowledge and Therapeutic Perspectives.

作者信息

Olas Beata, Białecki Jacek, Urbańska Karina, Bryś Magdalena

机构信息

University of Lodz, Department of General Biochemistry, Faculty of Biology and Environmental Protection, Lodz, Poland.

Medical University of Lodz, Faculty of Medicine, Lodz, Poland.

出版信息

Adv Nutr. 2021 Dec 1;12(6):2301-2311. doi: 10.1093/advances/nmab081.

DOI:10.1093/advances/nmab081
PMID:34245145
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8634323/
Abstract

Blue synthetic dyes are widely used in many industries. Although they are approved for use as food dyes and in cosmetics and some medicines, their impacts on consumer health remain unknown. Some studies indicate that 2 synthetic dyes, Blue No. 1 and Blue No. 2, may have toxic effects. It has therefore been suggested that these should be replaced with natural dyes; however, despite being nontoxic and arguably healthier than synthetic dyes, these compounds are often unsuitable for use in food or drugs due to their instability. Nevertheless, among the natural blue pigments, anthocyanins and genipin offer particular health benefits, as they are associated with the prevention of cardiovascular disease and have anticancer, neuroprotective, anti-inflammatory, and antidiabetic properties. This review summarizes the effects of blue food and drug colorings on health and proposes that synthetic colors should be replaced with natural ones.

摘要

蓝色合成染料在许多行业中广泛使用。尽管它们被批准用作食品染料、用于化妆品和一些药品中,但其对消费者健康的影响仍然未知。一些研究表明,两种合成染料,即亮蓝和靛蓝,可能具有毒性作用。因此,有人建议用天然染料取代它们;然而,尽管这些天然染料无毒且可以说比合成染料更健康,但由于其不稳定性,它们通常不适合用于食品或药品中。尽管如此,在天然蓝色色素中,花青素和京尼平具有特殊的健康益处,因为它们与预防心血管疾病有关,并且具有抗癌、神经保护、抗炎和抗糖尿病特性。这篇综述总结了蓝色食品和药物色素对健康的影响,并建议用天然色素取代合成色素。