基于头围估算经颅电刺激时的个体感应电场强度。

Estimation of individually induced e-field strength during transcranial electric stimulation using the head circumference.

机构信息

Department of Neurology, Universitätsmedizin Greifswald, Greifswald, Germany.

Berlin Institute of Health, Berlin, Germany; Institute of Biometry and Clinical Epidemiology, Charité - Universitätsmedizin, Berlin, Germany.

出版信息

Brain Stimul. 2021 Sep-Oct;14(5):1055-1058. doi: 10.1016/j.brs.2021.07.001. Epub 2021 Jul 8.

DOI:10.1016/j.brs.2021.07.001

PMID:34246820

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8497040/

Abstract

BACKGROUND

Head and brain anatomy have been related to e-field strength induced by transcranial electrical stimulation (tES). Individualization based on anatomic factors require high-quality structural magnetic resonance images, which are not always available. Head circumference (HC) can serve as an alternative means, but its linkage to electric field strength has not yet been established.

METHODS

We simulated electric fields induced by tES based on individual T1w- and T2w-images of 47 healthy adults, for four conventional ("standard") and four corresponding focal ("4x1") electrode montages. Associations of electric field strength with individual HC were calculated using linear mixed models.

RESULTS

Larger HC was associated with lower electric field strength across montages. We provide mathematical equations to estimate individual electric field strength based on the HC.

CONCLUSION

HC can be used as an alternative to estimate interindividual differences of the tES-induced electric field strength and to prospectively individualize stimulation dose, e.g., in the clinical context.

摘要

背景

头部和大脑解剖结构与经颅电刺激（tES）产生的电场强度有关。基于解剖因素的个体化需要高质量的结构磁共振图像，但并非总是可用。头围（HC）可以作为替代手段，但它与电场强度的联系尚未确定。

方法

我们基于 47 名健康成年人的个体 T1w 和 T2w 图像模拟了 tES 产生的电场，针对四种常规（“标准”）和四种相应的聚焦（“4x1”）电极排列。使用线性混合模型计算了电场强度与个体 HC 的相关性。

结果

更大的 HC 与各种电极排列中的较低电场强度相关。我们提供了基于 HC 估计个体电场强度的数学方程。

结论

HC 可用于替代估计 tES 诱导的电场强度的个体间差异，并前瞻性地个体化刺激剂量，例如在临床环境中。

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基于头围估算经颅电刺激时的个体感应电场强度。

Estimation of individually induced e-field strength during transcranial electric stimulation using the head circumference.

机构信息

Department of Neurology, Universitätsmedizin Greifswald, Greifswald, Germany.

Berlin Institute of Health, Berlin, Germany; Institute of Biometry and Clinical Epidemiology, Charité - Universitätsmedizin, Berlin, Germany.

出版信息

Brain Stimul. 2021 Sep-Oct;14(5):1055-1058. doi: 10.1016/j.brs.2021.07.001. Epub 2021 Jul 8.

DOI:10.1016/j.brs.2021.07.001

PMID:34246820

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8497040/

Abstract

BACKGROUND

METHODS

RESULTS

Larger HC was associated with lower electric field strength across montages. We provide mathematical equations to estimate individual electric field strength based on the HC.

CONCLUSION

HC can be used as an alternative to estimate interindividual differences of the tES-induced electric field strength and to prospectively individualize stimulation dose, e.g., in the clinical context.

摘要

背景

方法

结果

更大的 HC 与各种电极排列中的较低电场强度相关。我们提供了基于 HC 估计个体电场强度的数学方程。

结论

HC 可用于替代估计 tES 诱导的电场强度的个体间差异，并前瞻性地个体化刺激剂量，例如在临床环境中。

基于头围估算经颅电刺激时的个体感应电场强度。

Estimation of individually induced e-field strength during transcranial electric stimulation using the head circumference.

机构信息

出版信息

BACKGROUND

METHODS

RESULTS

CONCLUSION

背景

方法

结果

结论

相似文献

引用本文的文献

本文引用的文献

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基于头围估算经颅电刺激时的个体感应电场强度。

Estimation of individually induced e-field strength during transcranial electric stimulation using the head circumference.

机构信息

出版信息

BACKGROUND

METHODS

RESULTS

CONCLUSION

背景

方法

结果

结论