Song Bijia, Zhu Jun-Chao
Department of Anesthesiology, Shengjing Hospital of China Medical University, Shenyang, China.
Department of Anesthesiology, Beijing Friendship Hospital of Capital Medical University, Beijing, China.
Front Neurosci. 2021 Jun 25;15:590619. doi: 10.3389/fnins.2021.590619. eCollection 2021.
Cerebellar malfunctions significantly impact the regulation of the sleep-wakefulness transition. The possible mechanism for this effect is still unknown. Evidence on the role of cerebellar processing in the sleep-wake cycle is derived mainly from animal studies, and clinical management of the sleep-wake cycle is also challenging. The purpose of this review is to investigate the role of cerebellar activity during normal sleep and the association between cerebellar dysfunction and sleep disorders. Large-scale, multicenter trials are still needed to confirm these findings and provide early identification and intervention strategies to improve cerebellar function and the sleep quality of patients.
小脑功能障碍会显著影响睡眠-觉醒转换的调节。这种影响的可能机制尚不清楚。关于小脑处理在睡眠-觉醒周期中作用的证据主要来自动物研究，并且睡眠-觉醒周期的临床管理也具有挑战性。本综述的目的是研究正常睡眠期间小脑活动的作用以及小脑功能障碍与睡眠障碍之间的关联。仍需要大规模、多中心试验来证实这些发现，并提供早期识别和干预策略，以改善小脑功能和患者的睡眠质量。
