从早期到轻度阿尔茨海默病，总护理成本显著增加：ALSOVA 5 年随访。

Total cost of care increases significantly from early to mild Alzheimer's disease: 5-year ALSOVA follow-up.

机构信息

Department of Neurology, University of Eastern Finland, Kuopio, Finland.

Department of Health and Social Management, University of Eastern Finland, Kuopio, Finland.

出版信息

Age Ageing. 2021 Nov 10;50(6):2116-2122. doi: 10.1093/ageing/afab144.

DOI:10.1093/ageing/afab144

PMID:34255025

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8581391/

Abstract

INTRODUCTION

We studied the costs of formal and informal care in relation to Alzheimer's disease (AD) progression.

METHODS

231 persons with AD with a family caregiver were followed up for 5 years. The Clinical Dementia Rating Scale-Sum of Boxes (CDR-SB) was used to measure AD progression. Health and social care unit costs were used for formal care costs. An opportunity cost method for lost leisure time was applied to analyse the cost of informal care.

RESULTS

Total cost of care in early stage AD (CDR-SB ≤ 4) was 16,448€ (95% CI 13,722-19,716) annually. In mild (CDR-SB 4.5-9), moderate (CDR-SB 9.5-15.5) and severe (CDR-SB ≥ 16) AD, the total costs were 2.3, 3.4 and 4.4 times higher, respectively. A one-unit increase in CDR-SB increased the total, formal and informal costs by 15, 11 and 18%, respectively.

CONCLUSIONS

Compared to early AD, the costs of total, formal and informal care are remarkably higher already in mild AD. This finding emphasises early diagnosis, interventions and family support for persons with AD and their caregivers.

摘要

简介

我们研究了与阿尔茨海默病（AD）进展相关的正式和非正式护理的成本。

方法

231 名有家庭护理者的 AD 患者接受了 5 年的随访。使用临床痴呆评定量表-总盒数（CDR-SB）来衡量 AD 的进展。使用健康和社会护理单位成本来衡量正式护理成本。采用机会成本法分析了失去闲暇时间的非正式护理成本。

结果

早期 AD（CDR-SB≤4）的护理总成本为每年 16448 欧元（95%CI 13722-19716）。在轻度（CDR-SB 4.5-9）、中度（CDR-SB 9.5-15.5）和重度（CDR-SB≥16）AD 中，总成本分别高出 2.3、3.4 和 4.4 倍。CDR-SB 增加一个单位，总费用、正式费用和非正式费用分别增加 15%、11%和 18%。