Hollingsworth D R, Moore T R
Department of Reproductive Medicine, University of California, San Diego 92093.
Am J Obstet Gynecol. 1987 Dec;157(6):1359-63. doi: 10.1016/s0002-9378(87)80224-7.
In this study 42 pregnant women with type I diabetes and 28 nondiabetic controls were recruited to participate in a postprandial walking exercise program. Exercise patients were instructed to walk 20 minutes (1 mile) after each meal and were divided into two groups: group 1 were normal nondiabetic controls and group 2 were women with type I diabetes. There were two nonexercise comparison groups: group 3, nondiabetic controls, and group 4, women with type I diabetes. Diabetic women were followed weekly in an intensive perinatal program. Glycemic control was assessed by serial hemoglobin A1 concentration measurements, home blood glucose monitoring, 24-hour glucose profiles, and 24-hour quantitative urinary glucose loss. Glycemic control was modestly but not significantly superior in the diabetic exercise group 2 compared with the diabetic nonexercise group 4. Exercise was associated with lower fasting cholesterol and triglyceride values in both controls and diabetic women, with significantly lower fasting plasma triglyceride levels in the diabetic exercise group (p less than 0.02). There were no adverse effects of postprandial walking exercise in mothers or infants.
在本研究中，招募了42名患有I型糖尿病的孕妇和28名非糖尿病对照者，参与一项餐后步行锻炼计划。锻炼组患者被要求在每餐饭后步行20分钟（1英里），并分为两组：第1组为正常非糖尿病对照者，第2组为患有I型糖尿病的女性。有两个非锻炼对照组：第3组，非糖尿病对照者；第4组，患有I型糖尿病的女性。糖尿病女性在一个强化围产期项目中接受每周一次的随访。通过连续血红蛋白A1浓度测量、家庭血糖监测、24小时血糖谱和24小时定量尿糖丢失来评估血糖控制情况。与非锻炼的糖尿病第4组相比，锻炼的糖尿病第2组血糖控制有适度改善，但未达到显著差异。锻炼与对照组和糖尿病女性较低的空腹胆固醇及甘油三酯值相关，糖尿病锻炼组的空腹血浆甘油三酯水平显著降低（p<0.02）。餐后步行锻炼对母亲或婴儿均无不良影响。
