Wisbey A, Gregson P J, Tuke M
Southampton University, UK.
Biomaterials. 1987 Nov;8(6):477-80. doi: 10.1016/0142-9612(87)90085-8.
The requirements for successful joint arthroplasty are particularly exacting; a balanced combination of mechanical properties together with good biocompatibility are essential. Co-Cr based alloys have been used for many years on account of their relative inertness, good load bearing properties and excellent wear resistance. There is, however, concern that a slow accumulation of metal ions such as cobalt and chromium can lead to adverse clinical reactions; modern cementless fixation techniques may exacerbate this problem. In an attempt to reduce the release of potentially harmful metal ions from Co-Cr-Mo based surgical implants, a thin coating of TiN has been applied via Physical Vapour Deposition (PVD). In vitro corrosion performance has been investigated using electrochemical techniques, and also by atomic absorption analysis. The release of cobalt and chromium ions is shown to be reduced by the presence of the TiN coating, and these results are discussed in terms of the electrochemistry and microstructure of the coating and substrate.
成功进行关节置换术的要求极为严格；机械性能与良好生物相容性的平衡组合至关重要。钴铬基合金因其相对惰性、良好的承重性能和出色的耐磨性已被使用多年。然而，人们担心钴和铬等金属离子的缓慢积累会导致不良临床反应；现代非骨水泥固定技术可能会加剧这一问题。为了减少钴铬钼基外科植入物中潜在有害金属离子的释放，已通过物理气相沉积（PVD）法施加了一层薄的氮化钛涂层。已使用电化学技术以及原子吸收分析研究了体外腐蚀性能。结果表明，氮化钛涂层的存在可减少钴和铬离子的释放，并根据涂层和基底的电化学和微观结构对这些结果进行了讨论。
