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唑来膦酸给药后发生假性痛风1例。

A Case of Pseudogout Following Zoledronic Acid Administration.

作者信息

Hill Alexander C, Al Asmar Rania, Olajide Adenrele A, BenHamed Nesreen

机构信息

Pharmacy, Marshall University, Joan C. Edwards School of Medicine, Huntington, USA.

Internal Medicine, Marshall University, Joan C. Edwards School of Medicine, Huntington, USA.

出版信息

Cureus. 2021 Jun 13;13(6):e15627. doi: 10.7759/cureus.15627. eCollection 2021 Jun.

Abstract

Calcium pyrophosphate dihydrate (CPPD) deposition in the joints, often referred to as pseudogout, can lead to debilitating arthritis. Rare cases of pseudogout associated with bisphosphonate therapy have been reported in the literature, although the mechanism for this remains unclear. We report a case of a 53-year-old female who developed an acute pseudogout attack following administration of zoledronic acid for treatment of osteoporosis.

摘要

焦磷酸钙二水合物(CPPD)在关节中的沉积,通常被称为假性痛风,可导致使人虚弱的关节炎。文献中已报道了罕见的与双膦酸盐治疗相关的假性痛风病例,尽管其机制尚不清楚。我们报告一例53岁女性,在使用唑来膦酸治疗骨质疏松症后发生急性假性痛风发作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0514/8275062/af0e0f58d35f/cureus-0013-00000015627-i01.jpg

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