Wong Ronald Man Yeung, Qin Jianghui, Chau Wai Wang, Tang Ning, Tso Chi Yin, Wong Hiu Wun, Chow Simon Kwoon-Ho, Leung Kwok-Sui, Cheung Wing-Hoi
Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Sha Tin, Hong Kong SAR.
Department of Orthopaedics and Traumatology, Prince of Wales Hospital, Hospital Authority, Sha Tin, Hong Kong SAR.
Sci Rep. 2021 Jul 19;11(1):14650. doi: 10.1038/s41598-021-94199-0.
The objective of this study was to investigate the prognostic factors predicting the ambulation recovery of fragility hip fracture patients. 2286 fragility hip fracture patients were collected from the Fragility Fracture Registry in Hong Kong. Predictive factors of ambulation deterioration including age, gender, pre-operation American Society of Anesthesiologists grade, pre-fracture mobility, delay to surgery, length of stay, fracture type, type of surgery, discharge destination and complications were identified. Patients with outdoor unassisted and outdoor with aids ambulatory function before fracture had 3- and 1.5-times increased risk of mobility deterioration, respectively (Odds Ratio (OR) = 2.556 and 1.480, 95% Confidence Interval (CI) 2.101-3.111 and 1.246-1.757, both p < 0.001). Patients living in old age homes had almost 1.4 times increased risk of deterioration when compared to those that lived in their homes (OR = 1.363, 95% CI 1.147-1.619, p < 0.001). The risk also increased for every 10 years of age (OR = 1.831, 95% CI 1.607-2.086, p < 0.001). Patients in the higher risk ASA group shows a decreased risk of ambulation deterioration compared to those in lower risk ASA group (OR = 0.831, 95% CI 0.698-0.988, p = 0.038). Patients who suffered from complications after surgery did not increased risk of mobility decline at 1-year post-surgery. Delayed surgery over 48 h, delayed discharge (> 14 days), early discharge (less than 6 days), and length of stay also did not increased risk of mobility decline. Male patients performed worse in terms of their mobility function after surgery compared to female patients (OR = 1.195, 95% CI 1.070-1.335, p = 0.002). This study identified that better premorbid good function, discharge to old age homes especially newly institutionalized patients, increased age, lower ASA score, and male patients, correlate with mobility deterioration at 1-year post-surgery. With the aging population and development of FLS, prompt identification of at-risk patients should be performed for prevention of deterioration.
本研究的目的是调查预测脆性髋部骨折患者步行能力恢复的预后因素。从香港脆性骨折登记处收集了2286例脆性髋部骨折患者。确定了步行能力恶化的预测因素,包括年龄、性别、术前美国麻醉医师协会分级、骨折前活动能力、手术延迟时间、住院时间、骨折类型、手术方式、出院目的地和并发症。骨折前具备户外独立行走和户外借助辅助器具行走功能的患者,步行能力恶化的风险分别增加了2倍和1.5倍(优势比(OR)分别为2.556和1.480,95%置信区间(CI)为2.101 - 3.111和1.246 - 1.757,p均<0.001)。与居家生活的患者相比,居住在养老院的患者步行能力恶化的风险增加了近1.4倍(OR = 1.363,95% CI 1.147 - 1.619,p < 0.001)。年龄每增加10岁,风险也会增加(OR = 1.831,95% CI 1.607 - 2.086,p < 0.001)。与低风险ASA组的患者相比,高风险ASA组的患者步行能力恶化的风险降低(OR = 0.831,95% CI 0.698 - 0.988,p = 0.038)。术后出现并发症的患者在术后1年时步行能力下降的风险并未增加。手术延迟超过48小时、延迟出院(>14天)、提前出院(少于6天)以及住院时间也未增加步行能力下降的风险。术后男性患者的步行功能比女性患者差(OR = 1.195,95% CI 1.070 - 1.335,p = 0.002)。本研究发现,病前功能较好、出院至养老院尤其是新入住机构的患者、年龄增加、ASA评分较低以及男性患者,与术后1年时的步行能力恶化相关。随着人口老龄化和骨折联络服务(FLS)的发展,应及时识别高危患者以预防病情恶化。