Gatorade Sports Science Institute, PepsiCo Life Sciences, Global R&D, 5500 34th Street West, Bradenton, FL, 34210, USA.
PepsiCo Life Sciences, Global R&D, Purchase, NY, USA.
Geroscience. 2021 Oct;43(5):2485-2495. doi: 10.1007/s11357-021-00419-w. Epub 2021 Jul 20.
Skeletal muscle mass losses with age are associated with negative health consequences, including an increased risk of developing metabolic disease and the loss of independence. Athletes adopt numerous nutritional strategies to maximize the benefits of exercise training and enhance recovery in pursuit of improving skeletal muscle quality, mass, or function. Importantly, many of the principles applied to enhance skeletal muscle health in athletes may be applicable to support active aging and prevent sarcopenia in the healthy (non-clinical) aging population. Here, we discuss the anabolic properties of protein supplementation in addition to ingredients that may enhance the anabolic effects of protein (e.g. omega 3 s, creatine, inorganic nitrate) in older persons. We conclude that nutritional strategies used in pursuit of performance enhancement in athletes are often applicable to improve skeletal muscle health in the healthy older population when implemented as part of a healthy active lifestyle. Further research is required to elucidate the mechanisms by which these nutrients may induce favourable changes in skeletal muscle and to determine the appropriate dosing and timing of nutrient intakes to support active aging.
骨骼肌随年龄增长而减少与负面健康后果相关,包括罹患代谢疾病和丧失独立性的风险增加。运动员采用多种营养策略,以最大化运动训练的益处并促进恢复,从而改善骨骼肌质量、数量或功能。重要的是,许多用于增强运动员骨骼肌健康的原则可能适用于支持健康(非临床)老龄化人群的活跃老龄化和预防肌肉减少症。在这里,我们讨论了蛋白质补充的合成代谢特性,以及可能增强蛋白质(例如 omega 3、肌酸、无机硝酸盐)合成代谢作用的成分在老年人中的作用。我们得出的结论是,在追求运动员表现增强时使用的营养策略,当作为健康积极生活方式的一部分实施时,通常适用于改善健康老年人群的骨骼肌健康。需要进一步的研究来阐明这些营养素可能如何诱导骨骼肌产生有利变化的机制,并确定营养素摄入的适当剂量和时间,以支持活跃老龄化。