Department of Pathology and Laboratory Medicine, All India Institute of Medical Sciences, Bhubaneswar, India.
Diagn Cytopathol. 2021 Oct;49(10):1089-1098. doi: 10.1002/dc.24837. Epub 2021 Jul 21.
The International System for Reporting Serous Fluid Cytopathology (ISRSFC) was proposed by the International Academy of Cytology and the American Society of Cytopathology.
We have applied this system for reporting of pleural effusion cytology and report our experience.
All the pleural effusions from January 2019 to June 2020 were retrieved from the database. All these cases were reviewed and recategorized according to the proposed system of 5 categories: non-diagnostic (ND), negative for malignancy (NFM), atypia of uncertain significance (AUS), suspicious for malignancy (SFM), and malignant (MAL). The risk of malignancy (ROM) for each category was evaluated.
A total of 939 cases were studied. The age of patients ranged from 2 to 88 years, and the volume of fluid ranged from 1 to 600 ml. There were 41 ND (4.37%), 697 NFM (74.23%), 44 AUS (4.69%), 27 SFM (2.88%), and 130 MAL (13.84%) cases. The ROM for the categories were found to be 87.5%, 51.61%, 88.23%, 87.5%, and 100% respectively.
The ISRSFC is a user-friendly system for use in reporting of pleural fluid. The criteria for defining the various categories need to be further elaborative and stricter for this system to be more effective. More studies are required for the estimation of the ROM for each category.
国际浆膜腔液细胞病理学报告系统（ISRSFC）由国际细胞学学会和美国细胞病理学学会提出。
我们应用该系统报告胸腔积液细胞学，并报告我们的经验。
从 2019 年 1 月至 2020 年 6 月，从数据库中检索所有胸腔积液。根据提出的 5 类系统，对所有这些病例进行了回顾和重新分类：非诊断性（ND）、无恶性肿瘤（NFM）、非典型意义不确定（AUS）、疑似恶性肿瘤（SFM）和恶性肿瘤（MAL）。评估每个类别的恶性肿瘤风险（ROM）。
共研究了 939 例。患者年龄 2-88 岁，胸腔积液量 1-600ml。41 例 ND（4.37%）、697 例 NFM（74.23%）、44 例 AUS（4.69%）、27 例 SFM（2.88%）和 130 例 MAL（13.84%）。发现各分类的 ROM 分别为 87.5%、51.61%、88.23%、87.5%和 100%。
ISRSFC 是一种用户友好的胸腔液报告系统。需要进一步详细说明和严格定义各分类的标准，以使该系统更加有效。需要进一步研究以评估每个类别的 ROM。
